PELVIC ORGAN PROLAPSE

This study compares a newer surgical method (transobturator cystocele repair) with the standard native tissue repair for fixing a bladder prolapse (cystocele) in women aged 50 and older. About 592 participants will be followed to see which approach better corrects the prolapse an…

This study tests whether doing pelvic floor muscle exercises during a first pregnancy can reduce the chance of urinary incontinence, anal incontinence, and pelvic organ prolapse after childbirth. About 734 first-time mothers will be assigned to either a training program or standa…

This study looks at the best time to place a small mesh sling to treat stress urinary incontinence (leaking urine when coughing or laughing) during robotic surgery for pelvic organ prolapse. Doctors want to know if placing the sling before or after lifting the vagina works better…

This study looks at whether adding special 'hypopressive' exercises to standard pelvic floor muscle training can better improve muscle strength, reduce pain during sex, and boost quality of life in women with early-stage pelvic organ prolapse. About 46 married women aged 45-65 wi…

This study looks at whether a common surgery for pelvic organ prolapse can be safely performed without an overnight hospital stay. About 80 women with symptomatic prolapse will receive laparoscopic sacrocolpopexy (with or without robotic help) and be discharged the same day if th…

This study looks at whether taking sitz baths (soaking the pelvic area in warm water) after surgery for pelvic organ prolapse helps reduce pain and improve recovery. About 112 women will be randomly assigned to either a sitz bath routine or standard care. The main goal is to meas…

This study tests whether virtual group counseling (Shared Medical Appointments) helps patients feel more prepared and satisfied before pelvic organ prolapse surgery, compared to standard individual phone calls. About 106 adults scheduled for surgery at Cleveland Clinic will fill …

This study compares a new pessary system that women can insert and remove at home to standard pessary care for pelvic organ prolapse. About 200 women who have not used a pessary before will be randomly assigned to one of the two groups. The goal is to see if the new system improv…

This study follows 288 women recovering from pelvic organ prolapse surgery. Participants wear a wrist accelerometer and answer a daily recovery questionnaire. Some receive routine post-op instructions, others get an exercise-focused plan. The goal is to see which group feels "mos…

This study follows 100 women who had surgery for pelvic organ prolapse using GYNEMESH PS mesh. Researchers want to see how well the repair holds up about 7 years later. Participants will have a physical exam and fill out questionnaires about their symptoms and quality of life.

This study follows 1,000 women who have had surgery using Ethicon pelvic mesh products for stress urinary incontinence or pelvic organ prolapse. Researchers will check how well the mesh works and how safe it is over 5 to 10 years after surgery. The goal is to better understand lo…