New surgery aims to fix bladder prolapse without mesh

NCT ID NCT05602246

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a new surgical technique called transobturator cystocele repair (TOCR) to the standard anterior repair for fixing a cystocele, a type of pelvic organ prolapse where the bladder bulges into the vagina. About 592 women aged 50 and older with at least stage 2 prolapse will be randomly assigned to one of the two surgeries. The goal is to see which approach is safer and more effective at preventing the prolapse from coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Transobturator cystocele repair (TOCR) surgery

What this could lead to

If TOCR works better than standard repair, it could offer a more effective, less invasive surgical option for cystocele without using mesh.

What could go wrong

This is a surgical technique trial, not a drug. Success depends on surgeon skill and patient factors. The new method may not prove superior and could carry risks like any surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cystocele pelvic organ prolapse prolapse of female genital organ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Faculty of Medicine in Hradec Kralove, Charles University

    NOT_YET_RECRUITING

    Hradec Králové, 500 05, Czechia

    Contact Email: •••••@•••••

  • Faculty of Medicine in Pilsen, Charles University

    RECRUITING

    Pilsen, 30000, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Pardubice Region, Inc.

    NOT_YET_RECRUITING

    Pardubice, 530 03, Czechia

    Contact Email: •••••@•••••

  • Hospital na Bulovce, 1st Medical Faculty, Charles University

    NOT_YET_RECRUITING

    Prague, 18000, Czechia

    Contact Email: •••••@•••••

  • Košice Medical University

    NOT_YET_RECRUITING

    Košice, 040 11, Slovakia

    Contact Email: •••••@•••••

  • Medical Faculty, Ostrava University

    NOT_YET_RECRUITING

    Ostrava-Poruba, 708 52, Czechia

    Contact Email: •••••@•••••

  • Tomas Bata Regional Hospital in Zlin

    NOT_YET_RECRUITING

    Zlín, 762 75, Czechia

    Contact Email: •••••@•••••

  • Trenčianska univerzita Alexandra Dubčeka

    NOT_YET_RECRUITING

    Trenčín, 911 01, Slovakia

    Contact Email: •••••@•••••