New surgery aims to fix bladder prolapse without mesh

NCT ID NCT05602246

Recruiting now Disease control Sponsor: Charles University, Czech Republic Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a new surgical technique called transobturator cystocele repair (TOCR) to the standard anterior repair for fixing a cystocele, a type of pelvic organ prolapse where the bladder bulges into the vagina. About 592 women aged 50 and older with at least stage 2 prolapse will be randomly assigned to one of the two surgeries. The goal is to see which approach is safer and more effective at preventing the prolapse from coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Transobturator cystocele repair (TOCR) surgery
What this could lead to: If TOCR works better than standard repair, it could offer a more effective, less invasive surgical option for cystocele without using mesh.
What could go wrong: This is a surgical technique trial, not a drug. Success depends on surgeon skill and patient factors. The new method may not prove superior and could carry risks like any surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cystocele pelvic organ prolapse prolapse of female genital organ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CYSTOCELE CYSTOCELE AND INCOMPLETE UTEROVAGINAL PROLAPSE PELVIC ORGAN PROLAPSE

Contacts and locations

Locations

Faculty of Medicine in Hradec Kralove, Charles University
NOT_YET_RECRUITING

Hradec Králové, 500 05, Czechia
Faculty of Medicine in Pilsen, Charles University
RECRUITING

Pilsen, 30000, Czechia
Hospital Pardubice Region, Inc.
NOT_YET_RECRUITING

Pardubice, 530 03, Czechia
Hospital na Bulovce, 1st Medical Faculty, Charles University
NOT_YET_RECRUITING

Prague, 18000, Czechia
Košice Medical University
NOT_YET_RECRUITING

Košice, 040 11, Slovakia
Medical Faculty, Ostrava University
NOT_YET_RECRUITING

Ostrava-Poruba, 708 52, Czechia
Tomas Bata Regional Hospital in Zlin
NOT_YET_RECRUITING

Zlín, 762 75, Czechia
Trenčianska univerzita Alexandra Dubčeka
NOT_YET_RECRUITING

Trenčín, 911 01, Slovakia

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