PEDIATRIC

This study is testing whether a drug called aficamten is safe and effective for children and teenagers with a genetic condition that causes the heart muscle to thicken, making it harder to pump blood. Participants will take the drug or a placebo for 12 weeks, followed by a longer…

This study is testing if a drug called rapamycin can shrink severe lymphatic growths in the face and neck of children. It involves 28 young patients taking the oral medication for six months. Doctors will use MRI scans to see if the growths shrink by at least 20% and will also ch…

This study is testing which type of bandage works better for healing children's burns. Researchers are comparing a newer, natural gel dressing (chitosan) against the common silver-based dressing. They will measure how quickly the burns heal, how much scarring occurs, and the over…

This study aims to find the most effective surgery for pilonidal sinus, a painful skin condition near the tailbone that often comes back after treatment. It will compare four different surgical methods in 80 teenagers aged 12 to 18. The goal is to identify which procedure causes …

This study is testing whether a medication called tranexamic acid (TXA) can reduce blood loss and the need for blood transfusions in children undergoing major hip reconstruction surgery. Researchers will compare 400 children who receive TXA during surgery to those who do not. The…

This study is testing if adding a drug called dexmedetomidine to a standard pain-numbing injection (caudal block) can provide longer and better pain relief for children after open appendix removal surgery. It involves 60 children and will measure how long the pain relief lasts be…

This study aims to understand how brain networks change in children with dystonia, a movement disorder that causes involuntary muscle contractions. Researchers will measure brain and muscle activity in 75 children, including some with deep brain stimulation devices, to see how th…

This study aims to understand how common nerve pain is in children and teenagers who have had a limb amputated. Researchers will observe 50 participants, asking them questions about phantom limb pain, residual limb pain, and how it affects their daily life and independence. The g…