PEDIATRIC

This study is testing a new treatment for aggressive brain tumors that have come back or stopped responding to standard treatments in children and young adults. It involves a single injection of a modified virus (DNX-2401) directly into the tumor during a biopsy procedure. The ma…

This study aims to find the best way to manage pain after lower abdominal surgery in children aged 1 to 8. Researchers will compare two different numbing injections given during surgery: a common lower back (caudal) block and a newer back muscle (erector spinae plane) block. The …

This study aims to see if using special cards can make inhaler therapy easier for young children. Researchers will give children aged 4 to 6 either color-changing thermochromic cards or distraction cards during their breathing treatment. They will measure if using these cards red…

This study aims to find the best way to manage pain in children after a minimally invasive spleen removal surgery. Researchers will compare two different types of targeted nerve-block injections given during the operation to see which one provides better pain relief afterward. Th…

This study aims to see if visits from specially trained medical dogs can help children feel less scared and anxious while staying in the hospital. Researchers will compare dog visits to other calming activities like coloring or talking with a specialist. They will measure childre…

This study aims to understand how a common type of children's hernia surgery affects blood flow and oxygen levels in the brain. Researchers will monitor 32 children, aged 2-10, using special non-invasive sensors on the head during their operation. The goal is to gather informatio…

This study aims to understand how congenital hydronephrosis (swelling in a baby's kidney) naturally changes over the first three years of life. Researchers will follow 330 infants diagnosed before six months old, tracking whether the condition gets better, stays the same, or wors…

This study aims to create and test a structured follow-up system for children and young adults who have survived blood cancers like leukemia and lymphoma. It will track 400 survivors for three years to understand the long-term health problems they face and see if a new, organized…

This study aims to find the safest way to give anesthesia to children who need urgent surgery and have a full stomach. Researchers will compare two different techniques to see which one better prevents low oxygen levels during the process. The study will involve 100 children unde…

This study aims to establish normal reference ranges for blood clotting measurements in healthy children. Researchers will use the Quantra System to measure clotting factors in 240 pediatric patients undergoing elective procedures. The goal is to help doctors better identify abno…