New pain cocktail could help kids recover faster after appendix removal
NCT ID NCT07088900
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 41 times
Summary
This study looks at whether adding dexmedetomidine to the standard numbing drug bupivacaine in a caudal block (a type of pain shot near the tailbone) can give children longer pain relief after open appendix surgery. Sixty children will be randomly assigned to get either the combo or bupivacaine alone. The main goal is to see how long it takes before they need extra pain medicine.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ain Shams university hospitals
RECRUITINGCairo, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine added to bupivacaine
What this could lead to
If it works, this could provide longer-lasting pain relief and a smoother recovery for children after appendix surgery.
What could go wrong
This is a small, early-phase study with only 60 children, so results may not apply to everyone. There is also a risk of side effects like low blood pressure or slow heart rate from the added medication.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.