PAROXYSMAL ATRIAL FIBRILLATION
Clinical trials for PAROXYSMAL ATRIAL FIBRILLATION explained in plain language.
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Freezing heart tissue to stop AFib: new device under study
Disease control CompletedThis study tests a device that freezes small areas of heart tissue to treat paroxysmal atrial fibrillation (AFib), a condition where the heart beats irregularly. About 200 people with AFib that hasn't responded to medication will receive the procedure. Researchers will track safe…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New heart energy zaps AF better than standard treatment?
Disease control CompletedThis study tested a new way to treat paroxysmal atrial fibrillation (a type of irregular heartbeat) using pulsed field energy instead of standard radiofrequency. 292 adults with drug-resistant AF took part. The goal was to see if the new method is faster, safer, and more effectiv…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New heart procedure aims to tame atrial fibrillation without drugs
Disease control CompletedThis study tested a new device called the Volt PFA System, which uses pulsed field ablation to treat atrial fibrillation (AF), a common heart rhythm problem. Researchers enrolled 392 people with symptomatic AF that didn't respond to medication. The goal was to see if the procedur…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Could a cancer drug fix an irregular heartbeat?
Disease control CompletedThis study looked at whether Vidaza, a drug used for acute leukemia, could also help treat atrial fibrillation (an irregular heartbeat). The idea was that Vidaza might reverse certain DNA changes that lower the activity of a gene important for heart function. Only one person took…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New heart catheter shows promise for AFib patients
Disease control CompletedThis study tested a new device called the OMNYPULSE catheter with the TRUPULSE generator to treat paroxysmal atrial fibrillation (a type of irregular heartbeat). The goal was to see if it is safe and effective at isolating the veins that carry blood from the lungs to the heart. 1…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: Biosense Webster, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New ablation technique shows promise in Long-Term AFib control
Disease control CompletedThis study followed 364 people with paroxysmal atrial fibrillation (a type of irregular heartbeat) who had already received ablation treatment in a previous trial. Researchers compared a newer pulsed field ablation system with traditional thermal ablation to see how well each met…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New heart ablation device shows promise for common irregular heartbeat
Disease control CompletedThis study tested a new system that uses electrical pulses to treat a type of irregular heartbeat called paroxysmal atrial fibrillation (AF). The system includes a special catheter and generator designed to safely and effectively stop the faulty signals causing the condition. 150…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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New ablation catheter shows promise for treating irregular heartbeat
Disease control CompletedThis study tested a new type of catheter (a thin tube) that uses heat to destroy tiny areas of heart tissue causing irregular heartbeats in people with paroxysmal atrial fibrillation (AFib). The catheter has a cooling system to prevent overheating. The trial involved 415 particip…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New stepwise ablation method may reduce esophageal injury in AF patients
Disease control CompletedThis study tested a voltage-guided stepwise ablation strategy against the standard circumferential approach for treating atrial fibrillation. 130 adults with AF undergoing their first catheter ablation were randomly assigned to one of the two methods. The goal was to see if the s…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: Ajou University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Can a sleep machine tame a fluttering heart?
Disease control CompletedThis study looked at whether using a CPAP machine at night can reduce episodes of atrial fibrillation (a type of irregular heartbeat) in people who also have obstructive sleep apnea. Twenty-five adults with both conditions were enrolled. Half used CPAP while the other half were o…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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New heart ablation tracker shows promise for AFib patients
Disease control CompletedThis study tested a new tool called VISITAG that helps doctors track where they apply heat during a heart procedure for atrial fibrillation (AFib). The goal was to see if it makes the procedure safer and more effective at preventing irregular heartbeats for a year. 200 adults hav…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Sponsor: Giulio Zucchelli • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New heart catheter shows promise for stopping AFib episodes
Disease control CompletedThis study tested a special catheter and generator system to treat people with paroxysmal atrial fibrillation (AFib), a condition where the heart beats irregularly. The goal was to safely isolate the veins that trigger AFib and restore normal rhythm. 135 participants were treated…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: Biosense Webster, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Freezing out AFib: new device tested in Real-World study
Disease control CompletedThis study looked at how safe and effective a freezing treatment (cryoablation) is for people with a type of irregular heartbeat called paroxysmal atrial fibrillation (AFib). The treatment uses a device called POLARx to freeze heart tissue and stop the faulty signals causing AFib…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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New study tests better way to freeze away heart rhythm problem
Disease control CompletedThis study looked at 320 adults with paroxysmal atrial fibrillation (a type of irregular heartbeat) to compare two cryoballoon ablation techniques: freezing only the pulmonary veins versus freezing both the veins and the back wall of the heart's left upper chamber. The goal was t…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Sponsor: Sacramento EP Research • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Balloon catheter aims to zap away irregular heartbeat
Disease control CompletedThis phase 3 trial tested a special balloon catheter that uses radiofrequency energy to destroy tiny areas of heart tissue causing irregular heartbeats in people with symptomatic paroxysmal atrial fibrillation. The study enrolled 397 adults who had not responded to medication. Th…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: PHASE3 • Sponsor: Biosense Webster, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New ablation tools battle for better heart rhythm control
Disease control CompletedThis study tested two non-thermal ablation systems in 100 people with paroxysmal atrial fibrillation to see which works better and is safer. Patients were randomly assigned to one of the two devices, and their heart rhythms were monitored for a year. The goal was to find out whic…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: Alfried Krupp Krankenhaus • Aim: Disease control
Last updated Jun 26, 2026 18:19 UTC
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New heart mapping tech tested for AFib treatment
Disease control CompletedThis study tested a new mapping feature (FARAVIEW™) used with a pulsed field ablation catheter (FARAWAVE NAV™) to treat atrial fibrillation. Fifty patients with symptomatic AFib that didn't respond to medication were included. The goal was to see how well doctors could isolate th…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Jun 26, 2026 17:41 UTC
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New decision aid helps AF patients choose ablation with less regret
Symptom relief CompletedThis study tested whether showing patients with atrial fibrillation (AF) simple visual charts of common post-ablation symptoms could help them decide more confidently about undergoing the procedure. 75 adults with symptomatic AF who were considering catheter ablation used these d…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Small study tests if exercise eases heart flutter symptoms
Knowledge-focused CompletedThis pilot study looked at whether it's possible to run a larger trial comparing two types of exercise—moderate steady exercise and high-intensity interval training—on symptoms of atrial fibrillation (AF), a common heart rhythm problem. Researchers enrolled 25 men and women with …
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Which mapping system wins for repeat AF ablation?
Knowledge-focused CompletedThis study compared two heart-mapping systems, RHYTHMIA and CARTO, in 49 adults undergoing a repeat procedure for atrial fibrillation (AF). The goal was to see which system better finds gaps from previous ablations. The study did not test a new treatment but aimed to improve unde…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Heart reflex test may forecast AFib ablation success
Knowledge-focused CompletedThis study looked at 116 people with paroxysmal atrial fibrillation (AFib) who were scheduled for a heart ablation procedure. Researchers measured baroreflex sensitivity—a non-invasive test of the autonomic nervous system—before the procedure. They wanted to see if this measureme…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Bigger balloon, better burn? new study maps heart lesions
Knowledge-focused CompletedThis study tested a larger 31 mm cryoballoon in 20 patients with paroxysmal atrial fibrillation to see how much heart tissue it could freeze. Researchers used 3D maps before and after the procedure to measure the size of the treated area. The goal was to gather data to improve fu…
Matched conditions: PAROXYSMAL ATRIAL FIBRILLATION
Phase: NA • Sponsor: Erasmus Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC