Freezing heart tissue to stop AFib: new device under study

NCT ID NCT06170606

First seen Jun 24, 2026 · Last updated Jul 01, 2026 · Updated 4 times

Summary

This study tests a device that freezes small areas of heart tissue to treat paroxysmal atrial fibrillation (AFib), a condition where the heart beats irregularly. About 200 people with AFib that hasn't responded to medication will receive the procedure. Researchers will track safety and effectiveness for 12 months, looking for serious side effects and whether the heart stays in normal rhythm.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cardiac Cryoablation System (device that freezes heart tissue to stop abnormal signals)

What this could lead to

If successful, this could offer a safe, effective way to control paroxysmal atrial fibrillation without needing lifelong medication.

What could go wrong

This is a single-arm study with no comparison group, so results may be less definitive. Risks include serious complications like stroke, heart damage, or blood clots.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation paroxysmal atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aurora Health

    Grafton, Wisconsin, 53024, United States

  • Banner University Medical Center Phoenix

    Phoenix, Arizona, 85006, United States

  • Bethesda North Hospital

    Cincinnati, Ohio, 45242, United States

  • Intermountain Platte Valley Hospital

    Brighton, Colorado, 80601, United States

  • Mercy Gilbert Medical Center

    Gilbert, Arizona, 85297, United States

  • Pima Heart & Vascular Clinical Research

    Tucson, Arizona, 85718, United States

  • Prisma Health Richland Hospital

    Columbia, South Carolina, 29203, United States

  • St. Joseph's Hospital/BayCare Medical Group

    Tampa, Florida, 33607, United States

  • Torrance Memorial Medical Center

    Torrance, California, 90505, United States

  • University of Texas Medical Branch - Galveston

    Galveston, Texas, 77555, United States

  • Valley View Hospital

    Glenwood Springs, Colorado, 81601, United States