Freezing heart tissue to stop AFib: new device under study

NCT ID NCT06170606

Completed Disease control Sponsor: Boston Scientific Corporation Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 28, 2026 · Updated 6 times

Summary

This study tests a device that freezes small areas of heart tissue to treat paroxysmal atrial fibrillation (AFib), a condition where the heart beats irregularly. About 200 people with AFib that hasn't responded to medication will receive the procedure. Researchers will track safety and effectiveness for 12 months, looking for serious side effects and whether the heart stays in normal rhythm.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cardiac Cryoablation System (device that freezes heart tissue to stop abnormal signals)
What this could lead to: If successful, this could offer a safe, effective way to control paroxysmal atrial fibrillation without needing lifelong medication.
What could go wrong: This is a single-arm study with no comparison group, so results may be less definitive. Risks include serious complications like stroke, heart damage, or blood clots.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PAROXYSMAL ATRIAL FIBRILLATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

atrial fibrillation paroxysmal atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAROXYSMAL ATRIAL FIBRILLATION

Contacts and locations

Locations

Aurora Health

Grafton, Wisconsin, 53024, United States
Banner University Medical Center Phoenix

Phoenix, Arizona, 85006, United States
Bethesda North Hospital

Cincinnati, Ohio, 45242, United States
Intermountain Platte Valley Hospital

Brighton, Colorado, 80601, United States
Mercy Gilbert Medical Center

Gilbert, Arizona, 85297, United States
Pima Heart & Vascular Clinical Research

Tucson, Arizona, 85718, United States
Prisma Health Richland Hospital

Columbia, South Carolina, 29203, United States
St. Joseph's Hospital/BayCare Medical Group

Tampa, Florida, 33607, United States
Torrance Memorial Medical Center

Torrance, California, 90505, United States
University of Texas Medical Branch - Galveston

Galveston, Texas, 77555, United States
Valley View Hospital

Glenwood Springs, Colorado, 81601, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.