PARKINSON DISEASE (PD)

This study is testing whether injecting lab-grown brain cells into patients can help control early-onset Parkinson's disease. Researchers will give 90 participants a single injection of these cells and monitor their safety and effect on symptoms for a year. The goal is to see if …

This early-stage study is testing a new treatment called PDR-001, delivered by injection directly into the brain. The goal is to clear a harmful protein believed to drive Parkinson's disease progression, rather than just treating symptoms. Researchers will enroll 12 people with e…

This study is testing whether a supplement called D-serine can slow the progression of Parkinson's disease. Researchers will give 100 people with early Parkinson's either D-serine or a placebo for 58 weeks to see if it improves their symptoms and protects brain cells. The goal is…

This study is testing whether special 'smart socks' can accurately measure walking and balance problems in people with Parkinson's disease. Researchers will compare data from 60 people—some with Parkinson's and some healthy—during a single lab visit. The goal is to see if the soc…

This study aims to develop a simple blood test to detect Parkinson's disease in its earliest stages, before major symptoms appear. Researchers will follow 1,200 people (600 with Parkinson's and 600 without) for two years, analyzing tiny particles in their blood for specific prote…

This study is exploring whether a 6-week training program focused on empathy and self-compassion can improve quality of life for people with Parkinson's disease and their caregivers. Thirty participants will complete mindfulness, writing, and poetry exercises designed to build co…

This study is testing how safe and easy it is for people with Parkinson's disease to use a special leg sleeve at home. The sleeve uses gentle electrical stimulation to help with walking. Researchers will watch 10 participants to see if they can learn to use the device on their ow…

This study is testing if a 12-week exercise program can help improve walking and balance for people with moderate to advanced Parkinson's disease. The program combines physical training with mental tasks and is supervised by a therapist. Researchers will enroll 48 participants to…

This study is testing whether immersive virtual reality therapy can improve balance in people with Parkinson's disease. Fifty participants will be randomly assigned to receive either standard physical therapy or virtual reality therapy during their rehabilitation sessions. The re…

This study is testing whether a non-invasive, focused ultrasound device can reduce hand tremor in people whose shaking doesn't improve with medication. It will involve 12 adults with Parkinson's disease tremor, essential tremor, or dystonic tremor. Researchers will use the NaviFU…

This study is testing if a gentle, non-invasive brain stimulation can boost the benefits of a walking program for people with Parkinson's disease. Forty participants will be randomly assigned to receive either the real brain stimulation or a fake version while they complete the s…

This study is testing whether a daily amino acid supplement, designed specifically for people with Parkinson's disease, can improve their nutrition, physical function, and mental well-being. Researchers will compare the effects of the real supplement to a placebo (a look-alike wi…

This study aims to understand hearing problems in people with early-stage Alzheimer's or Parkinson's disease. Researchers will compare detailed hearing test results from 309 participants—some with these conditions and some healthy—to see if specific hearing issues are more common…

This study aims to understand how Parkinson's disease affects the muscles used for breathing. Researchers will use ultrasound to measure the thickness of abdominal breathing muscles in 36 patients at different stages of Parkinson's. They will then check if changes in these muscle…

This study is testing a new imaging method to see how Parkinson's disease and Lewy body dementia affect the nerves that control the heart. Researchers will compare heart scans from 20 people with these conditions to scans from people with other neurological diseases. The goal is …

This study is testing whether special 'smart socks' with built-in sensors can accurately measure walking and balance in people with Parkinson's disease. Researchers will compare the sock data to standard lab equipment to see if the socks are reliable. The goal is to see if the so…