Blood test could spot Parkinson's years before symptoms appear

NCT ID NCT06941012

Recruiting now Diagnosis Sponsor: Casa di Cura IGEA Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a blood test can detect Parkinson's disease early, before symptoms become severe. Researchers will measure specific proteins (α-synuclein) in tiny particles from nerve cells in the blood of 600 people with Parkinson's and 600 healthy controls. The goal is to create a non-invasive, affordable diagnostic tool that could lead to earlier treatment and better outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple blood test for early Parkinson's detection, allowing for earlier treatment and better disease management.
What could go wrong: This is an observational study, not a treatment trial. The test is still being validated and may not prove accurate enough for widespread use. Results are years away from clinical application.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autosomal dominant Parkinson disease 4 Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE (PD)

Contacts and locations

Locations

Aristotle University of Thessaloniki
RECRUITING

Thessaloniki, 54124, Greece
Asociacion Parkinson Madrid
RECRUITING

Madrid, 28014, Spain
Casa di Cura Igea
RECRUITING

Milan, Mi, 20144, Italy
Instytut Psychiatrii I Neurologii
RECRUITING

Warsaw, 02-957, Poland

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