Blood test could spot Parkinson's years before symptoms appear

NCT ID NCT06941012

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a blood test can detect Parkinson's disease early, before symptoms become severe. Researchers will measure specific proteins (α-synuclein) in tiny particles from nerve cells in the blood of 600 people with Parkinson's and 600 healthy controls. The goal is to create a non-invasive, affordable diagnostic tool that could lead to earlier treatment and better outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test for early Parkinson's detection, allowing for earlier treatment and better disease management.

What could go wrong

This is an observational study, not a treatment trial. The test is still being validated and may not prove accurate enough for widespread use. Results are years away from clinical application.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autosomal dominant Parkinson disease 4 Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aristotle University of Thessaloniki

    RECRUITING

    Thessaloniki, 54124, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Asociacion Parkinson Madrid

    RECRUITING

    Madrid, 28014, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Casa di Cura Igea

    RECRUITING

    Milan, Mi, 20144, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instytut Psychiatrii I Neurologii

    RECRUITING

    Warsaw, 02-957, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••