Magnetic pulses to the brain may unstick Parkinson's patients who freeze when walking
NCT ID NCT07731841
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
This trial investigates whether transcranial magnetic stimulation (TMS) can help people with Parkinson's disease who experience freezing of gait — a sudden inability to move their feet while walking. Participants first receive standard TMS to the motor cortex; those who don't improve enough then receive a combined stimulation targeting both the motor cortex and the cerebellum. The study aims to identify who benefits most from standard TMS and whether the extra cerebellar stimulation can help treatment-resistant patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- transcranial magnetic stimulation (TMS) applied to the motor cortex, spinal cord, or cerebellum
- What this could lead to
- If it works, this could offer a non-invasive treatment option for freezing of gait in Parkinson's disease, especially for those who don't improve with standard TMS.
- What could go wrong
- This is a small, early-stage study, and results may not apply to all patients. TMS can cause discomfort or headache, and the cerebellar stimulation approach is experimental.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Affiliated Hospital with Nanjing Medical University
Nanjing, Jiangsu, 210029, China
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