Brain implant that thinks for itself could transform Parkinson's care

NCT ID NCT07635823

Recruiting now Disease control Sponsor: Beijing Pins Medical Co., Ltd Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new type of deep brain stimulation (DBS) that automatically adjusts its settings based on real-time brain signals, unlike standard DBS which uses fixed stimulation. Sixty people with Parkinson's disease will have a special neurostimulator implanted and then experience both the adaptive and conventional modes in a randomized, double-blind crossover design. The goal is to see if the adaptive system improves daily 'on' time without troublesome movement side effects, motor symptoms, and quality of life compared to the standard approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: adaptive deep brain stimulation (aDBS) device
What this could lead to: If successful, this could offer Parkinson's patients a more personalized treatment that automatically adjusts stimulation to their needs, potentially improving symptom control and quality of life.
What could go wrong: This is a relatively small, early-stage trial (60 people) comparing two device modes, not a new drug. The benefits may be modest, and not everyone may respond well to the adaptive mode.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Dyskinesias Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE (PD)

Contacts and locations

Locations

Beijing Tiantan Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 10000, China
First Affiliated Hospital, Sun Yat-Sen University
NOT_YET_RECRUITING

Guangzhou, Guangdong, China
Nanjing Brain Hospital
RECRUITING

Nanjing, Jiangsu, China
Peking Union Medical College Hospital
NOT_YET_RECRUITING

Beijing, Beijing Municipality, China
Qilu Hospital of Shandong University
NOT_YET_RECRUITING

Jinan, Shandong, China
The First Affiliated Hospital of USTC (Anhui Provincial Hospital)
NOT_YET_RECRUITING

Hefei, Anhui, China
West China Hospital
NOT_YET_RECRUITING

Chengdu, Sichuan, China
Xiangya Hospital of Central South University
RECRUITING

Changsha, Hunan, China
Xuanwu Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 10000, China

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