Brain implant that thinks for itself could transform Parkinson's care
NCT ID NCT07635823
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new type of deep brain stimulation (DBS) that automatically adjusts its settings based on real-time brain signals, unlike standard DBS which uses fixed stimulation. Sixty people with Parkinson's disease will have a special neurostimulator implanted and then experience both the adaptive and conventional modes in a randomized, double-blind crossover design. The goal is to see if the adaptive system improves daily 'on' time without troublesome movement side effects, motor symptoms, and quality of life compared to the standard approach.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
adaptive deep brain stimulation (aDBS) device
What this could lead to
If successful, this could offer Parkinson's patients a more personalized treatment that automatically adjusts stimulation to their needs, potentially improving symptom control and quality of life.
What could go wrong
This is a relatively small, early-stage trial (60 people) comparing two device modes, not a new drug. The benefits may be modest, and not everyone may respond well to the adaptive mode.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beijing Tiantan Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 10000, China
Contact Phone: •••-•••-••••
Contact
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First Affiliated Hospital, Sun Yat-Sen University
NOT_YET_RECRUITINGGuangzhou, Guangdong, China
Contact
Contact
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Nanjing Brain Hospital
RECRUITINGNanjing, Jiangsu, China
Contact
Contact
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Peking Union Medical College Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, China
Contact
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Qilu Hospital of Shandong University
NOT_YET_RECRUITINGJinan, Shandong, China
Contact
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The First Affiliated Hospital of USTC (Anhui Provincial Hospital)
NOT_YET_RECRUITINGHefei, Anhui, China
Contact
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West China Hospital
NOT_YET_RECRUITINGChengdu, Sichuan, China
Contact
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Xiangya Hospital of Central South University
RECRUITINGChangsha, Hunan, China
Contact
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Xuanwu Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 10000, China
Contact
Contact Phone: •••-•••-••••