PARKINSON DISEASE (PD)

This study aims to see if people with Parkinson's disease can manage their own exercise schedules at home using a telerehabilitation system and get similar benefits to a supervised program. Researchers will compare two groups over 8 weeks to measure changes in movement, walking, …

This early-stage study is testing a new gene therapy called VGN-R08b for Parkinson's disease in people who have a specific genetic change (GBA1 mutation). The therapy is injected directly into the fluid around the brain. The main goals are to first check if it's safe and tolerabl…

This study aims to find out which type of exercise is most helpful for people with Parkinson's disease. Researchers will compare supervised programs of non-contact boxing, guided cycling, and traditional physical therapy over 8 weeks. They will measure how each program affects pa…

This study is testing if using data from a body-worn sensor (a smartwatch-like device) can help doctors better adjust Parkinson's medication for patients who experience motor fluctuations. The goal is to reduce the amount of time patients spend in the 'off' state, where symptoms …

This early-stage study aims to test the safety and initial effects of stem cells from umbilical cords in people with Parkinson's disease. Twenty participants will receive either the stem cells or a placebo, given through an IV and sometimes also as a nasal spray. The main goal is…

This study is testing whether a 16-week home exercise program, guided by a coach over video calls, can help people with Parkinson's disease. Fifty participants who are not currently very active will be randomly assigned to either do aerobic and strength exercises or a stretching …

This study is testing whether a simple, non-invasive treatment called remote ischemic conditioning (RIC) can help improve sleep and other non-motor symptoms in people with Parkinson's disease. For 7 days, 48 participants with Parkinson's and insomnia will use an arm cuff that bri…

This study is testing a new exercise program to help people with Parkinson's disease who experience slowness of movement (bradykinesia). Researchers will compare a standard physical therapy program to one that focuses on fast, powerful movements (muscle power training). The goal …

This study aims to understand if a specific brain function called 'inhibitory control'—the ability to stop or control actions—is connected to how well people with Parkinson's disease can adjust their walking to step over obstacles. Researchers will measure brain activity and walk…

This study aims to understand if a standard Parkinson's disease medication (Levodopa-Benserazide) has any effect on gum health and inflammation. Researchers will compare gum health and saliva samples from 136 people across four groups: those with Parkinson's and gum disease, thos…

This study aims to clarify whether eating nuts helps prevent major chronic diseases like diabetes, heart disease, cancer, and dementia. It will combine and analyze health data from over one million adults across the globe who have been tracked for at least five years. The goal is…