Parkinson's Patients' rhythm skills tested on and off medication

NCT ID NCT07647913

Not yet recruiting Knowledge-focused Sponsor: McMaster University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how dopamine levels affect the ability to keep a steady beat in people with early-stage Parkinson's disease. 34 participants will do simple tapping tasks both on their usual levodopa medication and after skipping it for 12 hours. The goal is to understand whether dopamine helps shield rhythm skills from distractions and allows people to adapt to changing speeds.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Levodopa withdrawal (withholding medication)
What this could lead to: If successful, this could help design better music- or rhythm-based therapies for movement problems in Parkinson's.
What could go wrong: This is a small, early-stage study (34 people) that only looks at short-term effects. It won't directly test a new treatment, so benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE (PD)

Contacts and locations

Locations

Psychology Building

Hamilton, Ontario, L8S 4L8, Canada

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Other studies related to the condition(s) this trial covers.