Could zapping the ear unlock Gut-Brain secrets in Parkinson's?
NCT ID NCT07673146
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study investigates how stimulating the vagus nerve through the ear affects stomach function and brain activity in people with Parkinson's disease. Participants receive non-invasive electrical stimulation via a device placed on the ear, and researchers measure stomach responses with MRI and brain activity with fMRI. The goal is to better understand gut-brain communication in Parkinson's, which may lead to new insights into the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
UROstim (non-invasive ear stimulation device)
What this could lead to
If successful, this could reveal how gut-brain signals influence Parkinson's symptoms, potentially pointing toward new non-drug therapies.
What could go wrong
This is an early exploratory study with only 45 participants, so results may not apply broadly. The stimulation is temporary and not intended as a treatment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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