Could a common supplement slow Parkinson's? new trial aims to find out

NCT ID NCT07312110

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether D-serine, a dietary supplement, can slow the progression of Parkinson's disease. One hundred people with early-stage Parkinson's will receive either D-serine or a placebo for 58 weeks. Researchers will measure changes in symptoms and brain scans to see if D-serine protects nerve cells and improves quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
D-serine (a dietary supplement)
What this could lead to
If it works, this could point toward a treatment that slows Parkinson's progression and reduces symptoms, helping people live better longer.
What could go wrong
This is an early Phase 2 trial with only 100 people. It may fail to show benefit, and D-serine might not work for everyone. Side effects are possible, though previous studies suggest it is safe.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Akershus University Hospital

    NOT_YET_RECRUITING

    Lørenskog, Akershus, 1478, Norway

  • Bodø Hospital (Nordland Hospital)

    NOT_YET_RECRUITING

    Bodø, Nordland, 8006, Norway

  • Førde Hospital

    NOT_YET_RECRUITING

    Førde, Vestland, 6812, Norway

  • Haugesund Hospital

    NOT_YET_RECRUITING

    Haugesund, Rogaland, 5528, Norway

  • Haukeland University Hospital

    RECRUITING

    Bergen, Vestland, 5021, Norway

  • Molde Hospital

    NOT_YET_RECRUITING

    Molde, Møre og Romsdal, 6412, Norway

  • Nevro Arendal Soerlandsklinikken

    RECRUITING

    Arendal, Agder, 4838, Norway

  • Oslo University Hospital

    RECRUITING

    Oslo, Oslo, 0450, Norway

  • University Hospital of North Norway

    NOT_YET_RECRUITING

    Tromsø, Troms, 9019, Norway

  • Vestre Viken Hospital

    NOT_YET_RECRUITING

    Drammen, Buskerud, 3004, Norway

  • Østfold Hospital

    NOT_YET_RECRUITING

    Sarpsborg, Østfold fylke, 1714, Norway

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