Could a common supplement slow Parkinson's? new trial aims to find out
NCT ID NCT07312110
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether D-serine, a dietary supplement, can slow the progression of Parkinson's disease. One hundred people with early-stage Parkinson's will receive either D-serine or a placebo for 58 weeks. Researchers will measure changes in symptoms and brain scans to see if D-serine protects nerve cells and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- D-serine (a dietary supplement)
- What this could lead to
- If it works, this could point toward a treatment that slows Parkinson's progression and reduces symptoms, helping people live better longer.
- What could go wrong
- This is an early Phase 2 trial with only 100 people. It may fail to show benefit, and D-serine might not work for everyone. Side effects are possible, though previous studies suggest it is safe.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Akershus University Hospital
NOT_YET_RECRUITINGLørenskog, Akershus, 1478, Norway
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Bodø Hospital (Nordland Hospital)
NOT_YET_RECRUITINGBodø, Nordland, 8006, Norway
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Førde Hospital
NOT_YET_RECRUITINGFørde, Vestland, 6812, Norway
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Haugesund Hospital
NOT_YET_RECRUITINGHaugesund, Rogaland, 5528, Norway
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Haukeland University Hospital
RECRUITINGBergen, Vestland, 5021, Norway
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Molde Hospital
NOT_YET_RECRUITINGMolde, Møre og Romsdal, 6412, Norway
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Nevro Arendal Soerlandsklinikken
RECRUITINGArendal, Agder, 4838, Norway
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Oslo University Hospital
RECRUITINGOslo, Oslo, 0450, Norway
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University Hospital of North Norway
NOT_YET_RECRUITINGTromsø, Troms, 9019, Norway
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Vestre Viken Hospital
NOT_YET_RECRUITINGDrammen, Buskerud, 3004, Norway
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Østfold Hospital
NOT_YET_RECRUITINGSarpsborg, Østfold fylke, 1714, Norway
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Parkinson's pain: could a new Add-On drug bring relief?
- Can virtual games retrain the brain to restore balance?
- High-Resolution brain scans aim to unmask Tau's role in Parkinson's
- Can brain stimulation sharpen Decision-Making in Parkinson's?
- Can Stem-Cell implants restore movement in Parkinson's?
- Magnetic pulses to the brain may unstick Parkinson's patients who freeze when walking