Stem cell injection aims to replace lost brain cells in Parkinson's
NCT ID NCT07166757
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a single injection of lab-grown nerve cells made from stem cells to treat early-onset Parkinson's disease. The cells are designed to replace the dopamine-producing neurons that are lost in Parkinson's. The trial has two phases: first, a small safety test in 6-12 people, then a larger blinded study in 81 people comparing the cell injection to a sham procedure. All participants will also take immunosuppressant drugs to prevent rejection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
human allogeneic induced pluripotent stem cell-derived dopaminergic neural progenitor cells
What this could lead to
If successful, this could point toward a cell-replacement therapy that restores dopamine-producing neurons and slows Parkinson's progression.
What could go wrong
This is an early-phase trial (Phase I/II) with a small number of participants, so safety and effectiveness are not yet proven. Participants also need to take immunosuppressants, which carry their own risks.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Huashan Hospital, Fudan University
RECRUITINGShanghai, Shanghai Municipality, 200040, China