PAIN

This study tested whether a 3D ultrasound device (Accuro) helps place epidurals more easily in obese pregnant women compared to the standard blind method. The trial planned to enroll 40 women with a BMI of 40 or higher who requested pain relief during labor. The study was termina…

This study tested an experimental drug called GSK3858279 to see if it could reduce moderate to severe knee pain from osteoarthritis. About 314 adults aged 40 to 80 took part. The trial was stopped early, so we don't have final results on how well the drug worked or its safety.

This study tested whether D-cycloserine, a drug that affects brain signaling, could reduce pain in people with chronic low back pain lasting at least 6 months. About 203 adults with moderate to severe pain were to receive either the drug or a placebo. The study was terminated ear…

This early-phase study tested whether taking ibuprofen (a pain reliever) and ondansetron (an anti-nausea drug) before a medical abortion (up to 70 days pregnant) could reduce pain and nausea and make the experience more satisfying. The trial planned to enroll 8 healthy, English-s…

This study tested an experimental drug called GSK3858279 in 147 adults with long-term nerve pain caused by diabetes. The goal was to see if the drug could reduce pain better than a placebo. The trial was stopped early, so final results are limited, but the data may still help res…

This study looked at whether cancer patients already taking strong opioids (like morphine) can stop taking paracetamol without their pain getting worse. Only 7 people took part before the study was stopped early. The goal was to see if paracetamol adds any extra benefit for pain …

This study looked at 91 premature babies (born before 36 weeks) to see if a heart rate measure (HFVI) and skin conductance can help assess pain as well as the standard behavioral scale (PIPP-R). The goal was to find more objective ways to measure pain in newborns who cannot speak…

This study tested a virtual reality training program for healthcare teams to improve care for new mothers and reduce pain disparities. About 66 participants, including doctors, nurses, and doulas, took part. The study was ended early, so results are limited.