OBESITY, MORBID

This early study is testing whether a small, implanted brain stimulator can help people who struggle with severe loss of control over eating. The device, similar to those used for epilepsy, is being tried in six people with severe obesity who have not been helped by surgery or ot…

This study compares two telemedicine approaches to help rural residents with obesity manage their weight over 18 months. One approach uses quarterly doctor visits, while the other adds group lifestyle coaching sessions via Zoom. Researchers want to see which method helps people l…

This study compares two types of intestinal bypass surgery performed after a previous stomach reduction surgery for severe obesity. Researchers want to see if a newer, simpler surgical connection causes fewer digestive problems and nutritional deficiencies than the standard metho…

This study is testing if a safe, injectable dye that glows under special light can help surgeons better see blood flow while connecting the stomach and intestine during gastric bypass surgery. The goal is to see if using this dye leads to fewer complications like ulcers, leaks, o…

This small pilot study is testing whether a less invasive procedure to reduce stomach size is safe and effective for weight loss in adolescents with obesity. Up to 10 teens will have the endoscopic procedure, which uses a scope instead of surgery, and will be closely monitored fo…

This study is testing an 8-week online program designed for couples where one person had weight loss surgery 1-3 years ago. The program uses positive psychology activities, like expressing gratitude and setting goals, to help improve mood, resilience, and relationship satisfactio…

This study analyzes existing medical records from 8,000 people who had weight-loss surgery at a specific medical center. The goal is to learn from past patients by comparing different surgical procedures. Researchers will look at how much weight people lost, any surgical complica…

This study aims to collect long-term data on 5,000 patients who have had endoscopic or surgical weight loss procedures. Researchers will track weight changes, health improvements, side effects, and costs over 10 years to better understand which treatments work best. The goal is t…

This study aims to collect and store biological samples from 500 people with obesity. The goal is to build a repository of blood, urine, and tissue to help researchers understand why weight loss treatments sometimes work or fail, and why weight is often regained. This is an obser…

This study aims to understand if bariatric (weight loss) surgery can help improve memory and thinking skills in people with severe obesity. Researchers will enroll 9,500 participants, some with and some without cognitive issues, to track changes in brain function after surgery. T…