Brain zapper for binge eating? tiny trial tests implant

NCT ID NCT03868670

Ongoing Disease control Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests a brain implant that monitors and stimulates brain activity to reduce loss-of-control eating in people with severe obesity who haven't been helped by other treatments. Only 6 participants will receive the device, and the main goal is to check safety and see if it works. It's a very small first step, so results won't be conclusive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: responsive neurostimulation device (RNS System)
What this could lead to: If it works, this could point toward a new treatment option for people with severe obesity who haven't been helped by other therapies.
What could go wrong: This is a very early, tiny study with only 6 people, focused on safety. It may not show clear benefit, and brain surgery carries risks like infection or side effects from the implant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

binge eating disorder morbid obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOSS OF CONTROL EATING OBESITY, MORBID

Contacts and locations

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Locations

Stanford University

Stanford, California, 94301, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19107, United States

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