OBESITY, MORBID
Clinical trials for OBESITY, MORBID explained in plain language.
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Weight-Loss drug tested for patients who regain weight after surgery
Disease control CompletedThis study looked at how the weight-loss medication tirzepatide works for people in two real-world situations: those who have regained a significant amount of weight after bariatric surgery, and those who need to lose weight before having obesity surgery. Researchers followed 254…
Matched conditions: OBESITY, MORBID
Sponsor: Azienda Sanitaria Locale Napoli 2 Nord • Aim: Disease control
Last updated Apr 01, 2026 21:41 UTC
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New surgery aims for better weight loss than gold standard
Disease control CompletedThis study compared two types of weight-loss surgery for people with severe obesity. It tested a newer procedure called SADI-S against the common standard, RYGB, to see which leads to more weight loss and fewer side effects over two years. Researchers followed 382 patients to mea…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Drug combo tested to tackle severe obesity and diabetes
Disease control CompletedThis study tested if adding the drug dapagliflozin to the common diabetes medication metformin helps people with severe obesity and either prediabetes or type 2 diabetes lose more weight. It involved 160 participants who were randomly assigned to take either metformin alone or th…
Matched conditions: OBESITY, MORBID
Phase: PHASE2, PHASE3 • Sponsor: Centro Medico Nacional Siglo XXI IMSS • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Could a buddy system boost weight loss surgery success?
Disease control CompletedThis study tested if having a support person, like a partner or friend, attend medical appointments with patients getting weight loss surgery could help. Researchers wanted to see if this support led to better weight loss, healthier eating, and more exercise after surgery compare…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Surgeons test 'Stomach Wrap' to lock in weight loss and stop heartburn
Disease control CompletedThis study tested a new surgical technique for people with severe obesity. During a common weight loss surgery, surgeons wrapped part of the stomach with the patient's own tissue instead of using an artificial band. The goal was to see if this 'FundoRing' technique helped patient…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: The Society of Bariatric and Metabolic Surgeons of Kazakhstan • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Ultrasound aimed to make spinal anesthesia easier for very obese moms
Symptom relief CompletedThis study tested if using an ultrasound machine to guide spinal anesthesia is better than the traditional 'feel for landmarks' method for very obese women (BMI 50+) having planned C-sections. It involved 60 women and measured which method was more successful on the first try, fa…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Karaman Training and Research Hospital • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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New nerve blocks could reduce opioid use after weight loss surgery
Symptom relief CompletedThis study compared two different nerve-block techniques for managing pain after weight loss surgery in obese patients. Researchers tested whether an ultrasound-guided erector spinae plane block (ESPB) or a modified thoracoabdominal nerve block (M-TAPA) provided better pain relie…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Kasr El Aini Hospital • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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New injection could slash pain pills after weight loss surgery
Symptom relief CompletedThis study tested a new type of nerve block injection to see if it could reduce pain and the need for strong opioid painkillers after weight loss surgery. Researchers compared the new injection, given during surgery, to standard pain control methods alone. The main goal was to se…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Samsun University • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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Scientists probe Surgery's hidden effect on hunger hormone
Knowledge-focused CompletedThis study aimed to understand how a common weight-loss surgery affects a hormone called Phoenixin-14, which is linked to appetite. Researchers measured the hormone levels in 36 adults with severe obesity before and after they had laparoscopic sleeve gastrectomy. The goal was to …
Matched conditions: OBESITY, MORBID
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists track chemical shifts after weight loss surgery
Knowledge-focused CompletedThis study aims to understand how weight loss surgery changes the levels of amino acids in the blood. Researchers will compare blood samples from 50 people having surgery with 50 healthy people over three months. The goal is to learn more about the body's metabolism after this ty…
Matched conditions: OBESITY, MORBID
Sponsor: Harran University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC