OBESITY, MORBID
Clinical trials for OBESITY, MORBID explained in plain language.
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New stomach wrap could improve gastric bypass results and reduce reflux
Disease control CompletedThis study tested a new surgical technique called FundoRing, where the surgeon wraps the unused part of the stomach around the new stomach pouch during gastric bypass. The goal is to improve weight loss and reduce bile reflux compared to the standard bypass. One thousand adults w…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: The Society of Bariatric and Metabolic Surgeons of Kazakhstan • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New surgical tweak may cut acid reflux after gastric sleeve
Disease control CompletedThis study tested whether adding a crural repair and gastropexy to standard sleeve gastrectomy reduces acid reflux in people with severe obesity. Fifty patients were randomly assigned to either the standard surgery or the enhanced version. After one year, the group with the extra…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Van Training and Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Magnets may offer a new way to boost weight loss after failed surgery
Disease control CompletedThis study tested a device that uses self-forming magnets to create new connections in the gut. It was done in 28 adults with severe obesity who had already had weight-loss surgery but did not lose enough weight. The goal was to see if the device is safe and works as intended. Th…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: GI Windows, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Drug combo shows promise for weight loss in severe obesity
Disease control CompletedThis study looked at whether adding dapagliflozin to metformin helps people with prediabetes or type 2 diabetes and severe obesity lose more weight than metformin alone. About 160 participants took either both drugs or just metformin for up to 12 months. The main goal was to see …
Matched conditions: OBESITY, MORBID
Phase: PHASE2, PHASE3 • Sponsor: Centro Medico Nacional Siglo XXI IMSS • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Bring a buddy to boost bariatric success?
Disease control CompletedThis study looked at whether having a partner or support figure attend clinic visits before and after bariatric surgery helps patients lose more weight and make healthier choices. 63 adults seeking weight-loss surgery were randomly assigned to bring a support person or not. Resea…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Newer Weight-Loss surgery may beat the gold standard
Disease control CompletedThis study compared two types of weight-loss surgery: the newer SADI-S and the standard RYGB. Researchers wanted to see which one leads to more weight loss after two years. The trial involved 382 adults with severe obesity and measured safety and nutritional effects as well.
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 26, 2026 14:45 UTC
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Super obese moms: study finds ideal spinal anesthesia dose for safer C-Sections
Symptom relief CompletedThis study aimed to find the right dose of a spinal anesthesia drug (bupivacaine) for women with a BMI over 50 undergoing a planned C-section. Researchers tested different doses in 45 women to see which dose worked best without needing extra pain relief. The goal is to improve sa…
Matched conditions: OBESITY, MORBID
Phase: PHASE4 • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Ultrasound may help super obese moms get safer spinal anesthesia
Symptom relief CompletedThis study tested whether using ultrasound to guide the needle for spinal anesthesia works better than the traditional method of feeling for landmarks in super obese women (BMI 50 or higher) having a planned C-section. Sixty women participated, and the main goal was to see if the…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Karaman Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Nerve block showdown: which works best for pain after obesity surgery?
Symptom relief CompletedThis study compared two ultrasound-guided nerve block techniques—erector spinae plane block and modified thoracoabdominal nerve block—for pain control in 40 obese patients undergoing laparoscopic sleeve gastrectomy. The goal was to see which method delays the need for rescue pain…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Kasr El Aini Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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New pain block may cut opioid use after gastric sleeve surgery
Symptom relief CompletedThis study tested whether a specific nerve block, called a rectointercostal fascial plane block, could reduce pain and the need for strong painkillers after laparoscopic sleeve gastrectomy. Fifty-six adults undergoing weight-loss surgery were randomly assigned to receive either t…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Samsun University • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Weight-Loss drug shows promise for regain after gastric sleeve
Knowledge-focused CompletedThis completed study looked at how tirzepatide, a weight-loss drug, works in real-world settings for two groups: people who regained weight after gastric sleeve surgery, and those preparing for obesity surgery. Researchers tracked weight and metabolic changes over 6 months in 254…
Matched conditions: OBESITY, MORBID
Sponsor: Azienda Sanitaria Locale Napoli 2 Nord • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Sleeve surgery may alter appetite hormone levels
Knowledge-focused CompletedThis study looked at 36 adults with severe obesity who had laparoscopic sleeve gastrectomy, a type of weight-loss surgery. Researchers measured blood levels of a hormone called Phoenixin-14, which is thought to influence appetite, before and after the procedure. The goal was to s…
Matched conditions: OBESITY, MORBID
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Bariatric Surgery's hidden effect on blood amino acids revealed
Knowledge-focused CompletedThis study measured amino acid levels in the blood of 50 people before and after bariatric surgery, comparing them to 50 healthy individuals. The goal was to see how surgery affects metabolism over three months. It is an observational study, not testing a new treatment.
Matched conditions: OBESITY, MORBID
Sponsor: Harran University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC