New Stomach-Stitching procedure could help obese teens lose weight without surgery
NCT ID NCT06914765
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study is testing whether a procedure called endoscopic sleeve gastroplasty (ESG) is safe and helpful for weight loss in 10 obese adolescents aged 12-17. Instead of traditional weight-loss surgery, doctors use a device inserted through the mouth to stitch the stomach smaller. Participants will be monitored overnight and followed long-term to see if they lose weight and have fewer obesity-related health issues.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Endoscopic Sleeve Gastroplasty (ESG) procedure using the Apollo Endosurgery ESG System
- What this could lead to
- If successful, this could offer a less invasive weight-loss option for teens with obesity, potentially reducing obesity-related health problems.
- What could go wrong
- This is a very small pilot study with only 10 participants, so results may not apply to all teens. The procedure carries risks like any medical intervention, and long-term effectiveness is unknown.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Other studies related to the condition(s) this trial covers.
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