New Stomach-Stitching procedure could help obese teens lose weight without surgery
NCT ID NCT06914765
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study is testing whether a procedure called endoscopic sleeve gastroplasty (ESG) is safe and helpful for weight loss in 10 obese adolescents aged 12-17. Instead of traditional weight-loss surgery, doctors use a device inserted through the mouth to stitch the stomach smaller. Participants will be monitored overnight and followed long-term to see if they lose weight and have fewer obesity-related health issues.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Endoscopic Sleeve Gastroplasty (ESG) procedure using the Apollo Endosurgery ESG System
What this could lead to
If successful, this could offer a less invasive weight-loss option for teens with obesity, potentially reducing obesity-related health problems.
What could go wrong
This is a very small pilot study with only 10 participants, so results may not apply to all teens. The procedure carries risks like any medical intervention, and long-term effectiveness is unknown.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States