MORBID OBESITY

This study compares two versions of gastric bypass surgery for people with severe obesity. One method uses fixed lengths for the rerouted intestine, while the other customizes the lengths based on each patient's total small bowel length. The goal is to see if the customized appro…

This study looks at whether people who take GLP-1 receptor agonists (like Ozempic or Wegovy) should continue them after having bariatric surgery. Researchers will compare weight loss, blood sugar control, gut health, and hunger in 150 adults who either keep taking the drug or sto…

This study compares two different doses of the blood thinner bemiparin to see which works better at preventing dangerous blood clots in people with severe obesity after surgery. About 2,400 participants will be enrolled. The goal is to find the safest and most effective dose for …

This study tests a new, personalized version of a weight-loss surgery called SADI-S. Surgeons will measure each patient's small intestine and adjust the bypass length to maximize weight loss while lowering the risk of vitamin deficiencies. The study includes 40 adults with obesit…

This study follows 40 women with severe obesity who are scheduled for weight loss surgery. Researchers will measure changes in sexual function, sex hormone levels, mood, and quality of life before surgery and 6 months after. Partners will also report on their own sexual health. T…

This study follows 1,000 people who had bariatric surgery 5 years ago to learn why some maintain significant weight loss while others do not. Researchers will track weight, type of surgery, and other factors to improve patient counseling and tailor surgical choices. The goal is t…

This study looks at genetic and chemical markers in fat tissue from 500 people with severe obesity who are having weight-loss surgery. Researchers collect a small amount of belly fat during the operation and take blood samples afterward. The goal is to understand why some patient…

This study looks at 50 adults having either sleeve gastrectomy or gastric bypass to see if routine stool tests can reveal differences in gut function after surgery. Participants provide stool and blood samples before and 6 months after their operation. Researchers will check for …

This study follows 35 people with severe obesity who are having mini-gastric bypass surgery. Researchers want to see how the surgery changes body composition and improves related health issues like type 2 diabetes, sleep apnea, high blood pressure, and fatty liver disease. The go…

This study will test if weight-loss surgery can improve thinking skills like memory and attention. Researchers will use a virtual reality game and standard tests to measure brain function in 42 adults with severe obesity before and after surgery. The goal is to see if losing weig…

This study follows 300 people who are having weight-loss (metabolic) surgery to see how their gut bacteria change over time and how those changes relate to heart health, diabetes, and cholesterol. Participants provide blood and stool samples before surgery and at several follow-u…

This study looks at children with ROHHAD syndrome, a rare condition that causes rapid weight gain and breathing problems. Researchers will take blood samples to create special cells in the lab and study their genetic activity. The goal is to understand what goes wrong in the body…