MORBID OBESITY
Clinical trials for MORBID OBESITY explained in plain language.
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Sleeve surgery may help you walk better, study finds
Disease control CompletedThis study tested whether sleeve gastrectomy (a weight-loss surgery) improves walking ability in people with severe obesity. 99 adults with a BMI over 35 or 40 took a 6-minute walk test before surgery and again 6 months after. Researchers also measured quality of life and overall…
Matched conditions: MORBID OBESITY
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated May 17, 2026 04:35 UTC
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Smartphone app boosts Pre-Surgery weight loss in obesity study
Disease control CompletedThis study tested whether a mobile app (Care4Today®) helps people with severe obesity lose more weight before gastric bypass surgery compared to standard care. 142 adults aged 18-65 who qualified for surgery used the app or followed the usual pre-surgery plan. The goal was to see…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Hospital Universitari de Bellvitge • Aim: Disease control
Last updated May 17, 2026 04:32 UTC
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New weight loss surgery shows promise in Head-to-Head trial
Disease control CompletedThis study tested a newer, simpler weight loss surgery called SADI-S against a standard, more complex one (BPD-DS) in 62 adults with severe obesity. The goal was to see if SADI-S is safer and works as well for weight loss and related health problems like diabetes. Researchers mea…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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Can we skip opioids after Weight-Loss surgery? new study says maybe
Symptom relief CompletedThis study tested whether using no opioids during weight-loss surgery (opioid-free anesthesia) works as well as standard opioid-based anesthesia for controlling pain afterward. Sixty adults with severe obesity having laparoscopic bariatric surgery were randomly assigned to one of…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Hospital dos Lusíadas • Aim: Symptom relief
Last updated May 17, 2026 04:15 UTC
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Pre-Surgery mist may steady heart and pressure in obese patients
Symptom relief CompletedThis study tested whether breathing in a mist of dexmedetomidine before surgery could prevent dangerous spikes in heart rate and blood pressure during intubation and the start of laparoscopic bariatric surgery. 90 obese adults (BMI 30-45) took part. The goal was to see if this si…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Tanta University • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Lidocaine infusion may cut opioid use after bariatric surgery
Symptom relief CompletedThis study tested whether giving the numbing drug lidocaine continuously through a vein during weight-loss surgery could reduce pain and the need for strong painkillers afterward. 180 adults scheduled for bariatric surgery took part. Researchers measured how much pain medicine th…
Matched conditions: MORBID OBESITY
Phase: PHASE3 • Sponsor: University Hospital, Caen • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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New nerve block eases pain after gastric sleeve surgery
Symptom relief CompletedThis study tested a nerve block called the external oblique intercostal block to manage pain after laparoscopic sleeve gastrectomy in 20 obese patients. The goal was to see how well it numbs the belly area and reduces the need for strong painkillers in the first day after surgery…
Matched conditions: MORBID OBESITY
Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated May 07, 2026 18:43 UTC
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Can tracking movement improve life for those with severe obesity?
Knowledge-focused CompletedThis study looked at how physical activity relates to quality of life and mental health in adults with severe obesity (BMI over 40). Participants wore activity monitors for 6 weeks to track their movement and sedentary time. The goal was to understand these connections, not to pr…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 17, 2026 04:34 UTC
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Breathing or not? study finds safer way to intubate obese patients
Knowledge-focused CompletedThis study looked at 725 severely obese adults (BMI 35 or higher) to find the safest way to place a breathing tube during surgery. Researchers compared two methods: one where patients received face mask ventilation during the procedure and one where they did not. The goal was to …
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 04:14 UTC
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Weight-Loss surgery may change how blood thinners work
Knowledge-focused CompletedThis study looked at how the blood thinner rivaroxaban acts in people with severe obesity and in those who have had weight-loss surgery (gastric bypass or sleeve gastrectomy). 67 participants took rivaroxaban for 8 days, and researchers measured drug levels and blood clotting. Th…
Matched conditions: MORBID OBESITY
Phase: PHASE1 • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Stomach scans after bariatric surgery may predict weight regain
Knowledge-focused CompletedThis study looked at 46 people with severe obesity who had either gastric bypass or sleeve gastrectomy. Researchers used a special CT scan with gas to measure stomach volume 3 and 12 months after surgery. The goal was to see if an enlarged stomach pouch is linked to weight regain…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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When you eat may change your gut bugs, study finds
Knowledge-focused CompletedThis study examined how the number of meals per day and the timing of calories affect the types of bacteria in the gut. Researchers compared 23 adults with morbid obesity to 11 non-obese adults. No treatment or diet was given—only baseline data was analyzed to understand links be…
Matched conditions: MORBID OBESITY
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC