MORBID OBESITY

This completed pilot study tested whether transferring gut bacteria from lean donors or from people who had gastric bypass surgery could improve metabolism in 29 obese adults with prediabetes or diabetes. Participants received fecal transplants, and researchers measured changes i…

This study followed 543 adults aged 18-60 who had bariatric surgery at four hospitals in Norway. Each hospital used a different surgical method, allowing researchers to compare how well each approach helped with weight loss and type 2 diabetes remission. The goal was to find whic…

This study compared two weight loss surgeries for people with severe obesity: SASI and SAPI. Researchers looked at costs, weight loss, and safety in 68 adults aged 18-65. The goal was to see which surgery is more affordable and effective for long-term weight control.

This study looked at whether giving a single dose of gabapentin before laparoscopic sleeve gastrectomy (weight-loss surgery) helps protect kidney function in people with severe obesity. 90 patients with normal kidney function were enrolled. Researchers measured kidney markers lik…

This study compared two types of weight loss surgery in 80 adults with severe obesity. The goal was to see which surgery leads to better weight loss, improves health problems like diabetes and high blood pressure, and has fewer complications. Participants were followed after surg…

This study compared two types of weight-loss surgery in 256 adults with severe obesity. The goal was to see if a newer, simpler surgery (Omega Loop bypass) works as well as the standard Roux-en-Y gastric bypass, with fewer side effects. Participants were followed for two years to…

This study compares a newer weight-loss surgery called SADI-S to an older, more complex one called BPD-DS in 62 adults with severe obesity. The goal is to see if SADI-S is safer and just as effective for long-term weight loss and managing related health problems like diabetes. Re…

This study tested whether sleeve gastrectomy, a type of weight-loss surgery, improves walking ability in people with severe obesity. About 99 participants completed a 6-minute walk test before and 6 months after surgery. Researchers also measured quality of life and overall healt…

This study tested whether adding a drug called dexmedetomidine to a standard numbing medicine (bupivacaine) could improve pain control after weight loss surgery in severely obese patients. 78 adults having laparoscopic bariatric surgery received an ultrasound-guided nerve block w…

This study tested whether a mobile app (Care4Today®) helps people with severe obesity lose weight before gastric bypass surgery. 142 adults used either the app or standard care. The goal was to see if the app leads to more weight loss and better patient knowledge and satisfaction…

This study tested whether avoiding opioids during weight-loss surgery leads to less pain and fewer side effects like nausea. Sixty adults having laparoscopic bariatric surgery were randomly assigned to receive either opioid-free anesthesia (using other drugs) or standard opioid-b…

This study tested whether giving lidocaine through a vein during weight-loss surgery helps patients recover faster and need less strong pain medicine. 180 adults scheduled for bariatric surgery received either lidocaine or a placebo (salt water). Researchers measured how much pai…

This study looked at whether a specific nerve block (external oblique intercostal block) can reduce pain after laparoscopic sleeve gastrectomy, a weight-loss surgery. Twenty patients aged 18-65 participated. Researchers measured how much the block numbed the belly area and how mu…

This study tested whether giving a medicated mist (dexmedetomidine) before surgery could prevent dangerous spikes in heart rate and blood pressure when placing a breathing tube in 90 obese patients undergoing laparoscopic bariatric surgery. The approach aims to make the procedure…

This study used ultrasound to measure the optic nerve sheath (the lining around the eye nerve) in 56 adults having laparoscopic bariatric surgery. The goal was to see how brain pressure changes during surgery due to gas inflation and body positioning. No drug or treatment was tes…

This study looked at whether placing patients in a specific position (head up, feet down) before starting laparoscopic weight-loss surgery could reduce pressure on the brain. Researchers measured the optic nerve sheath diameter, an indicator of brain pressure, in 90 patients. The…

This study tested a technique to help doctors insert a breathing tube in very obese patients having weight-loss surgery. The method uses a laryngeal mask airway as a temporary helper to keep oxygen flowing while the doctor prepares for the main tube. Thirty-six patients took part…

This study looked at how physical activity relates to quality of life and mental health in 38 adults with severe obesity (BMI over 40). Participants wore activity monitors for 6 weeks to track sitting, standing, and movement. The goal was to see if simply monitoring activity coul…

This study looked at whether using a face mask to help obese patients breathe during a short pause in anesthesia makes intubation safer. Over 700 patients with a BMI of 35 or higher took part. The goal was to see which method leads to fewer complications like low oxygen levels or…

This study looked at 80 severely obese adults having laparoscopic sleeve gastrectomy (weight-loss surgery). Researchers measured heart electrical activity and blood pressure as patients were moved into different positions during the operation. The goal was to understand how posit…

This completed study looked at how the number of meals per day and the timing of energy intake influence gut microbiome composition in both morbidly obese and non-obese adults. Researchers analyzed baseline data from 34 participants (11 non-obese, 23 morbidly obese) to compare th…

This study looked at how the blood thinner rivaroxaban behaves in people with severe obesity or after bariatric surgery (gastric bypass or sleeve gastrectomy). Researchers gave 67 participants rivaroxaban daily for 8 days and measured drug levels and blood clotting. The goal is t…

This completed study looked at how the body digests and uses food during weight loss from bariatric surgery. Researchers used advanced 'omics' techniques to track nutrients in 7 participants. The goal was to understand why weight loss varies between people and to generate ideas f…

This study tracked 46 people with severe obesity who had gastric bypass or sleeve gastrectomy. Researchers used a special CT scan with gas to measure stomach volume at 3 and 12 months after surgery. The goal was to see if stomach enlargement is linked to weight regain, which coul…