MORBID OBESITY
Clinical trials for MORBID OBESITY explained in plain language.
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Weight-loss surgery prep trial pulled before it even started
Disease control TerminatedThis study aimed to see if blocking blood vessels to part of the stomach (bariatric embolization) could help super obese patients lose weight before sleeve gastrectomy surgery, potentially lowering surgical risks. It planned to enroll patients with a BMI over 50 and at least thre…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 27, 2026 13:08 UTC
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Blocking stomach blood flow to fight obesity: a new approach?
Disease control TerminatedThis study planned to test a procedure called bariatric embolization for people with morbid obesity who cannot have standard weight-loss surgery. The procedure involves injecting tiny particles into blood vessels near the stomach to reduce blood flow, which may lower hunger hormo…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: IHU Strasbourg • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Magnetic gut device could revolutionize Weight-Loss surgery
Disease control OngoingThis study tests a new magnetic device that creates connections between parts of the gut during weight-loss surgery. The goal is to see if it is safe and works as intended in 28 adults with severe obesity. If successful, it may offer a simpler way to perform these surgeries.
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: GI Windows, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Keto diet showdown: can a Very-Low-Calorie version beat the mediterranean diet for Long-Term weight loss?
Disease control OngoingThis study looks at whether a very-low-calorie ketogenic diet (VLCKD) helps people with severe obesity and metabolic syndrome lose more weight and improve heart health over three years compared to a standard Mediterranean diet. About 100 adults aged 55-75 will be randomly assigne…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Istituto Auxologico Italiano • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Exercise after Weight-Loss surgery: a boost for body and mind?
Symptom relief TerminatedThis study looks at whether two types of exercise training can improve body composition, heart and lung function, and quality of life in people who have had bariatric surgery. Researchers will compare high-intensity interval training (HIIT) and moderate-intensity continuous train…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Universidad Católica del Maule • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New anesthesia combo may cut opioid use after weight loss surgery
Symptom relief OngoingThis study tests whether a mix of ketamine and dexmedetomidine (ketodex) can reduce the need for strong painkillers after laparoscopic sleeve gastrectomy in obese patients. Eight adults with a BMI over 35 are randomly assigned to receive either ketodex or standard opioid-based an…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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New study aims to find the best Weight-Loss surgery for fewer side effects
Symptom relief OngoingThis study compares two types of weight-loss surgery—sleeve gastrectomy alone versus sleeve gastrectomy with transit bipartition—to see which leads to fewer cases of dumping syndrome (nausea, diarrhea, dizziness after eating) and better quality of life. Researchers will follow 20…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Mina Kamal Gergis Erian • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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New study aims to find best way to insert breathing tubes in obese patients
Knowledge-focused OngoingThis study looks at how head and neck position (sniffing vs. ramped) and the type of blade used on a video laryngoscope affect how quickly a breathing tube can be placed in 140 severely obese patients (BMI 40 or higher) undergoing elective surgery. The goal is to find the best co…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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No-scope stomach check: magnetic camera tested for pre-surgery screening
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests whether a swallowable camera capsule, controlled by magnets from outside the body, can safely and effectively examine the stomach and esophagus in 30 people preparing for weight loss surgery. Participants swallow the capsule after fasting, and a surgeon guides it…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Jerry Dang • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Obesity lung pressure study pulled before starting
Knowledge-focused TerminatedThis study aimed to measure pressure inside the chest (pleural pressure) in people with morbid obesity using a low-dose CT scan and a thin balloon placed in the esophagus. Researchers planned to compare 6 people with a BMI over 40 to 6 people with a BMI under 30. The study was wi…
Matched conditions: MORBID OBESITY
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Teen Weight-Loss surgery: hidden bone risks revealed?
Knowledge-focused OngoingThis study looks at how two types of weight-loss surgery affect bone health in teenagers and young adults aged 13-21. Researchers will measure changes in bone density and strength over two years in 240 participants, comparing those who had surgery with those who did not. The goal…
Matched conditions: MORBID OBESITY
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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8-year study reveals which weight-loss surgery is kinder to your esophagus
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 75 people who had either sleeve gastrectomy or gastric bypass for severe obesity. Researchers track acid reflux symptoms, esophageal damage, and other measures for 8 years using tests like endoscopy and pH monitoring. No new treatments are given—it's purely obs…
Matched conditions: MORBID OBESITY
Sponsor: Clinica Gastrobese • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC