Keto diet showdown: can extreme Low-Calorie plan beat mediterranean for Long-Term weight loss?

NCT ID NCT05781269

First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 23 times

Summary

This study compares a very-low-calorie ketogenic diet (VLCKD) to a standard Mediterranean diet in 100 adults with severe obesity and metabolic syndrome. Researchers will track weight, blood sugar, cholesterol, blood pressure, and artery health over 36 months to see which diet leads to better long-term control of weight and heart disease risk factors.

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Contacts and locations

Locations

  • Istituto Auxologico Italiano

    Milan, 20145, Italy

Conditions

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