New surgery may offer safer weight loss for the severely obese

NCT ID NCT02792166

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a newer weight-loss surgery called SADI-S to an older, more complex one called BPD-DS in 62 adults with severe obesity. The goal is to see if SADI-S is safer and just as effective for long-term weight loss and managing related health problems like diabetes. Researchers will track complications, weight changes, and side effects over five years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SADI-S (a type of weight-loss surgery that combines stomach reduction with intestinal bypass)

What this could lead to

If successful, SADI-S could offer a safer, simpler surgical option for lasting weight loss and control of obesity-related conditions like diabetes.

What could go wrong

This is a small, single-center study comparing two surgeries, so results may not apply broadly. Both procedures carry risks like malnutrition, bowel issues, and surgical complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metabolic syndrome X morbid obesity Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • McGill University Health Center

    Montreal, Quebec, H3G 1A4, Canada