METASTATIC PANCREATIC CANCER

This study looks at how safe and effective the diabetes drug glipizide is for lowering blood sugar in people with pancreatic cancer. About 29 adults with active pancreatic cancer and high blood sugar will take glipizide, and their glucose levels will be measured before and after …

This study tests a combination of two drugs, atezolizumab and cabozantinib, in 30 people with advanced pancreatic cancer that has spread and stopped responding to standard treatments. The goal is to see if the combo can shrink tumors or slow the disease. Researchers will also che…

This study tests a drug called ceralasertib, either alone or combined with olaparib or durvalumab, in people with advanced solid tumors like kidney, bladder, pancreatic, endometrial, and prostate cancers. The goal is to see if these combinations can shrink tumors or slow their gr…

This study tests a modified chemotherapy regimen for people aged 65 and older with newly diagnosed metastatic pancreatic cancer. The treatment alternates between two drug combinations (FOLFOX and FOLFIRI) to see if it is easier to tolerate than the standard FOLFIRINOX regimen. Th…

This study was designed to test a new drug, GFH375, in people with advanced pancreatic cancer that has a specific genetic change (KRAS G12D) and has already been treated. The goal was to see if the drug could shrink tumors or slow the disease. However, the trial was withdrawn bef…

This study tests a new drug called zolbetuximab, which targets a protein (CLDN18.2) found in most pancreatic cancers. It is given along with standard chemotherapy to people whose pancreatic cancer has spread. The goal is to see if adding zolbetuximab helps people live longer and …

This study tests whether a pancreatic enzyme replacement called pancrelipase can help maintain or improve body weight in people with metastatic pancreatic cancer. About 17 participants will receive either the enzyme or a placebo, and researchers will measure changes in body mass …

This study tests a new approach for advanced pancreatic cancer that cannot be removed by surgery. Doctors place a special device that releases alpha radiation directly into the tumor. The goal is to see if this procedure is safe and possible for patients. About 37 adults with adv…

This early-stage trial tests an experimental drug called OMO-103, which targets a cancer-driving protein called MYC, combined with standard chemotherapy in 26 people with metastatic pancreatic cancer. The main goals are to check safety and how well the body handles the drug, whil…

This study aimed to test a new two-step PET imaging method to locate cancer cells that make a protein called CA19-9. It was designed for people with pancreatic, bladder, or gastrointestinal cancers. However, the study was withdrawn before enrolling any participants, so no results…

This study aimed to see if a food supplement called ARACOMPLEX could help maintain quality of life in patients with advanced or metastatic pancreatic cancer who are receiving chemotherapy. The supplement contains maca extract, vitamins, and minerals. The study was withdrawn befor…