New drug IPH5301 targets tough cancers in first human trial

NCT ID NCT05143970

First seen Mar 27, 2026 · Last updated May 01, 2026 · Updated 4 times

Summary

This early-phase study tests a new drug called IPH5301 in people with advanced solid tumors that have spread. The drug aims to block a protein (CD73) that helps cancers hide from the immune system. The study first finds a safe dose of IPH5301 alone, then tests it combined with chemotherapy and trastuzumab in HER2-positive breast cancer patients. About 27 participants will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, France

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.