METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Clinical trials for METASTATIC CLEAR CELL RENAL CELL CARCINOMA explained in plain language.
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Kidney cancer trial: does surgery plus immunotherapy beat drugs alone?
Disease control Recruiting nowThis study is for people with kidney cancer that has spread to other parts of the body. It compares two standard treatments: immunotherapy drugs alone versus immunotherapy plus surgery to remove the affected kidney. The goal is to see if adding surgery helps people live longer. A…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Gut bacteria may boost immunotherapy in kidney cancer trial
Disease control Recruiting nowThis early-phase study tests whether adding a live bacteria product (EXL01) to standard immunotherapy (nivolumab + ipilimumab) is safe and helps control metastatic kidney cancer. About 33 adults with advanced renal cell carcinoma will receive either the standard drugs alone or wi…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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New combo therapy aims to slow advanced kidney cancer
Disease control Recruiting nowThis study tests whether adding the experimental drug casdatifan to the standard drug cabozantinib helps people with advanced clear cell kidney cancer live longer without their cancer growing. About 720 adults whose cancer worsened after prior immunotherapy will receive either ca…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE3 • Sponsor: Arcus Biosciences, Inc. • Aim: Disease control
Last updated May 06, 2026 16:02 UTC
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Fiber gel boosts cancer immunotherapy in new kidney cancer trial
Disease control Recruiting nowThis study tests whether adding inulin gel, a common fiber supplement, to standard immunotherapy drugs (ipilimumab and nivolumab) can help control advanced kidney cancer. About 55 adults with cancer that has spread or is locally advanced will receive the combination. The goal is …
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated May 05, 2026 12:06 UTC
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Tumor tissue study aims to predict cancer treatment success
Knowledge-focused Recruiting nowThis study collects tissue samples from people with various advanced or early-stage cancers to train a new diagnostic platform called Elephas. The goal is to see how accurately it can predict whether a patient will respond to immunotherapy or chemoimmunotherapy. About 324 partici…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Kidney cancer imaging study could unlock smarter drug combos
Knowledge-focused Recruiting nowThis early-phase study looks at how the drug belzutifan affects a protein called CAIX in clear cell kidney cancer that has spread. Twelve patients will get PET scans before and after four weeks of belzutifan to measure changes. The goal is not to treat the cancer directly, but to…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE1 • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated May 04, 2026 16:23 UTC