METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Clinical trials for METASTATIC CLEAR CELL RENAL CELL CARCINOMA explained in plain language.
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Could a One-Time treatment give kidney cancer patients a year off drugs?
Disease control Not yet recruitingThis study tests whether giving focused radiation or surgery to all visible tumors (both the original kidney tumor and its metastases) can allow people with advanced kidney cancer to stop all cancer treatments for at least a year. Participants must have stable or partially improv…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Gut bacteria boost may resensitize kidney tumors to immunotherapy
Disease control Not yet recruitingThis study tests whether altering gut bacteria can restore the effectiveness of immunotherapy in people with advanced kidney cancer. About 33 adults will receive a bowel cleanse, a live bacterial supplement, and then a combination of immunotherapy drugs. The goal is to see if thi…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: Jinling Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Could a probiotic boost a cancer drug? new trial tests the combo
Disease control Not yet recruitingThis phase 2 trial tests whether adding a probiotic capsule (MO-03) to the drug zanzalintinib can help treat metastatic kidney cancer that has worsened after immunotherapy. About 34 adults with advanced clear cell renal cell carcinoma will receive both treatments. The goal is to …
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Can a smaller dose of this cancer drug still work? new trial aims to find out
Disease control Not yet recruitingThis phase 2 trial is testing whether a lower dose of the immunotherapy drug nivolumab, given less often, can still control cancer in people with various advanced or metastatic cancers. The goal is to see if a cheaper, more accessible regimen works as well as the standard high-co…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New combo therapy targets Hard-to-Treat cancers
Disease control Not yet recruitingThis early-phase study tests a new drug combination (L19IL2 plus ruxolitinib) in people with advanced kidney, pancreatic, or colorectal cancers that have stopped responding to standard treatments. The main goals are to find a safe dose and check for side effects. About 96 partici…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE1 • Sponsor: Philogen S.p.A. • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Timing is everything: new trial tests surgery before or after immunotherapy for kidney cancer
Disease control Not yet recruitingThis clinical trial is for adults with metastatic clear cell kidney cancer. It compares having surgery to remove the kidney tumor either before or after starting immunotherapy drugs (ipilimumab and nivolumab). The goal is to see which timing helps people live longer without the c…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Cold sore virus modified to fight kidney cancer in new trial
Disease control Not yet recruitingThis phase 2 trial tests a combination of RP2 (a modified herpes simplex virus that targets and destroys tumor cells) and tivozanib (a drug that blocks tumor blood vessel growth) in 35 patients with metastatic kidney cancer that worsened after immunotherapy. The goal is to see if…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New scan could reveal hidden kidney cancer
Diagnosis Not yet recruitingThis early-phase study tests a new imaging agent called RYZ512 in 10 people with advanced clear cell kidney cancer that has spread. The agent is designed to attach to a protein (CAIX) found on these cancer cells, making them show up on scans. The goal is to see if it is safe and …
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: EARLY_PHASE1 • Sponsor: RayzeBio, Inc. • Aim: Diagnosis
Last updated Jun 28, 2026 00:00 UTC