METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Clinical trials for METASTATIC CLEAR CELL RENAL CELL CARCINOMA explained in plain language.
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Could a cheaper, easier dose of immunotherapy work just as well?
Disease control Not yet recruitingThis study tests whether giving a lower dose of the immunotherapy drug nivolumab less often can still control advanced cancers that have spread or can't be removed surgically. The goal is to make treatment more affordable and accessible worldwide. About 50 adults with various can…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 17, 2026 05:51 UTC
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Virus-Immunotherapy combo shows promise in kidney cancer trial
Disease control Not yet recruitingThis study tests whether adding a lab-modified virus (VSV-IFNβ-NIS) to standard immunotherapy drugs (ipilimumab and nivolumab) can shrink tumors in people with advanced or metastatic clear cell renal cell carcinoma. The virus is designed to kill cancer cells without harming norma…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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Cold sore virus modified to fight kidney cancer in new trial
Disease control Not yet recruitingThis study tests a new treatment for advanced kidney cancer that has spread and worsened after immunotherapy. The treatment combines a modified cold sore virus (RP2) that attacks tumor cells and activates the immune system, with a targeted drug (tivozanib) that blocks tumor growt…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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Gut bacteria may supercharge immunotherapy in kidney cancer trial
Disease control Not yet recruitingThis phase III trial tests whether adding a live biotherapy called MO-03 to standard immunotherapy can help control advanced or metastatic clear cell renal cell carcinoma. MO-03 is designed to improve gut health, which may make immunotherapy work better. About 718 participants wi…
Matched conditions: METASTATIC CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 12, 2026 13:40 UTC