LYMPHOMA NON-HODGKIN

This early-stage trial is testing a new drug called TLN-121, alone or with other treatments, in about 180 people whose Non-Hodgkin Lymphoma has returned or not responded to prior therapies. The main goals are to check the drug's safety and how the body processes it, while also lo…

This early-phase study is testing a new experimental drug called JNJ-95566692, a trispecific antibody designed to attach to three different targets on lymphoma cells and immune cells to help the body fight the cancer. The study includes about 130 adults with B-cell non-Hodgkin ly…

This early-stage trial tests a new drug, ONM-501, injected directly into tumors, either alone or with another drug (cemiplimab), for people with advanced solid tumors or lymphomas that have not responded to other treatments. The study aims to find the safest dose and check for si…

This study tests whether the drug epcoritamab can help people with follicular lymphoma whose cancer did not completely go away after standard first treatment. About 35 adults with advanced-stage disease will receive epcoritamab as a second-line therapy. The main goal is to see ho…

This study tests a new treatment called JNJ-90014496 (prizlo-cel) for adults with B-cell non-Hodgkin lymphoma that has come back or not responded to other treatments. The therapy uses a patient's own immune cells, which are modified in a lab to better recognize and attack cancer …

This study tests a new type of immunotherapy for children and young adults (ages 3-39) with B-cell cancers like leukemia or lymphoma that have come back or not responded to standard treatments. The therapy uses the patient's own immune cells, which are modified in a lab to target…

This study tests whether a 12-week program of short, frequent activity breaks can help newly diagnosed lymphoma patients on chemotherapy. Researchers want to see if reducing long periods of sitting can improve heart health and lessen drug side effects. The study involves 24 adult…

This study looks at whether a connected scale can help track the health of 30 people with lymphoma or multiple myeloma who are getting chemotherapy. Patients weigh themselves daily at home for about 7 weeks, and the care team gets alerts if something changes, like sudden weight g…

This study collects tumor tissue from people with Hodgkin's or non-Hodgkin's lymphoma to learn more about the cancer cells. Participants must already be scheduled for a routine procedure to remove lymph nodes. No treatment is given; the goal is to better understand the disease.

This study is testing whether an artificial intelligence system can detect when lymphoma patients are not taking their oral medications as prescribed. Researchers will enroll 210 adults with non-Hodgkin lymphoma and use AI algorithms to analyze patient data and predict non-compli…

This study looks at whether cancer drugs that target specific gene changes in a tumor can help people with advanced cancers that have not responded to standard treatments. About 720 adults with solid tumors, multiple myeloma, or certain lymphomas will receive a drug matched to th…

This study looks at whether giving targeted drugs based on a tumor's specific gene changes can help people with advanced cancer who have run out of standard treatments. It includes adults and teens with solid tumors, multiple myeloma, or non-Hodgkin lymphoma. The goal is to learn…

This study collects blood, bone marrow, and tumor samples from 500 adults with cancer or pre-cancerous conditions. Researchers will use these samples to learn more about how cancers grow and why they respond differently to treatments. The goal is to develop more effective therapi…

This study looks at why some families have more blood cancers like lymphoma, leukemia, and myeloma. Researchers will study the genes and environment of 3000 people who have at least two living relatives with these cancers. The goal is to find inherited factors that raise risk, no…

This study collects blood, urine, bone marrow, and tissue samples from adults with lymphoid cancers or precancerous conditions. The goal is to help researchers better understand these diseases, which may lead to new ways to diagnose or treat them. No treatment is given as part of…