LYMPHOMA, NON-HODGKIN

This is the first human study of a new experimental drug called JNJ-95566692, a triple-target antibody designed to fight B-cell non-Hodgkin lymphoma. The main goal is to find safe and tolerable doses, both alone and when combined with another drug, for people whose cancer has ret…

This study is testing whether the drug epcoritamab can help people with follicular lymphoma whose cancer did not completely disappear after their initial treatment. The drug works by activating the immune system to attack cancer cells. About 35 adults who had a partial response o…

This study aims to see if matching existing cancer drugs to the specific genetic changes found in a person's tumor can help control advanced cancers. It is for adults with certain advanced solid tumors, lymphoma, or multiple myeloma who have run out of standard treatment options.…

This is a first-in-human study to find a safe and effective dose of a new drug called ONM-501. The drug is injected directly into tumors and is being tested alone and in combination with an approved immunotherapy drug (cemiplimab) in adults with advanced cancers that have stopped…

This study is testing a new type of personalized immune cell therapy called prizlo-cel for adults with B-cell non-Hodgkin lymphoma that has returned or not responded to previous treatments, or for those with newly diagnosed high-risk disease. The therapy involves collecting a pat…

This early-stage trial is testing a new drug called TLN-121 for people with non-Hodgkin lymphoma that has come back or hasn't responded to previous treatments. The main goals are to find a safe dose and see how the body processes the drug, both when given alone and when combined …

This study aims to monitor the long-term safety of the drug pirtobrutinib in people with previously treated blood cancers like chronic lymphocytic leukemia and lymphoma. It is only open to a small group of 13 people who are already benefiting from the drug in a previous trial. Pa…

This study is testing a new, experimental CAR-T cell therapy designed to fight two targets (CD19 and CD22) on cancer cells at once. It is for children and young adults (ages 3-39) whose B-cell leukemia or lymphoma has come back or hasn't responded to standard treatments. Doctors …

This study is testing whether a smart scale that patients use at home can help doctors remotely monitor adults with lymphoma or myeloma who are getting chemotherapy. For about 7 weeks, 30 patients will weigh themselves daily. The scale sends data to the medical team, who can get …

This study is testing whether a simple 12-week program of short activity breaks is helpful for people newly diagnosed with lymphoma who are receiving chemotherapy. Researchers want to see if interrupting long periods of sitting can improve heart health and reduce some side effect…

This study collects blood, tissue, and other samples from adults with cancer or pre-cancerous conditions. The goal is to understand how cancer works and why treatments affect people differently. Researchers will bank these samples for future lab studies to help develop better imm…

This study aims to better understand how lymphoma grows and spreads by collecting and analyzing tumor tissue samples. Researchers will study the biology of lymphoma cells from patients with Hodgkin's or non-Hodgkin's lymphoma. The knowledge gained may help develop future treatmen…

This study aims to collect blood, tissue, and fluid samples from adults with lymphoma, multiple myeloma, or related blood cancers. The goal is to help researchers better understand the biology of these diseases in the lab. This is a sample collection study only and does not provi…

This study aims to learn from real-world experience by observing how well FDA-approved targeted cancer drugs work for patients with advanced solid tumors, lymphoma, or multiple myeloma. It enrolls over 4,000 patients whose tumors have specific genetic changes that suggest a drug …

This study aims to understand why certain blood and lymph cancers sometimes run in families. Researchers are enrolling families where at least two blood relatives have been diagnosed with these cancers. The goal is to learn how genetics and environmental factors might work togeth…