Which pneumonia vaccine works best for lymphoma patients? new study aims to find out

NCT ID NCT04460235

Recruiting now Disease control Sponsor: Poitiers University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two pneumococcal vaccination strategies in 160 adults with lymphoma who have had chemotherapy. One group gets two vaccines (Prevenar 13 followed by Pneumovax 23), while the other gets a single newer vaccine (Prevenar 20). Researchers will measure immune responses at several time points to see which approach provides better protection against pneumococcal disease. The goal is to improve vaccination guidelines for this vulnerable population.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pneumococcal vaccines (Prevenar 13, Pneumovax 23, and Prevenar 20)
What this could lead to: If successful, this could show which vaccine schedule offers better protection against serious pneumococcal infections for people with lymphoma.
What could go wrong: This is a phase 4 study with 160 participants, so results may not apply to all patients. The immune response in lymphoma patients can be weak, and the study compares two strategies rather than testing a new drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma follicular lymphoma lymphoma lymphoma, non-Hodgkin, familial non-Hodgkin lymphoma streptococcal pneumonia pneumococcal infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LYMPHOMA, NON-HODGKIN STREPTOCOCCUS PNEUMONIAE VACCINE

Contacts and locations

Locations

CHU Bordeaux
TERMINATED

Bordeaux, France
CHU Limoges
RECRUITING

Limoges, France
CHU Poitiers
RECRUITING

Poitiers, France
CHU Tours
RECRUITING

Tours, France
Ch Perigueux
RECRUITING

Périgueux, France
Chu Angers
RECRUITING

Angers, France
Chu Nantes
TERMINATED

Nantes, France

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