LYMPHOMA, NON-HODGKIN

This early-stage study tested a new combination of two immunotherapy drugs (relatlimab and nivolumab) in children and young adults whose Hodgkin or non-Hodgkin lymphoma had come back or did not respond to standard treatments. The main goals were to find a safe dose and see if the…

This large, completed Phase 3 trial tested whether adding a new drug called copanlisib to the standard treatment rituximab was better at delaying the return or worsening of cancer in patients with a slow-growing type of non-Hodgkin's lymphoma that had come back. It involved 458 a…

This study tested a new drug called mosunetuzumab, both alone and combined with another drug (atezolizumab), for people with B-cell non-Hodgkin lymphoma or chronic lymphocytic leukemia that had come back or stopped responding to prior treatments. The main goals were to find safe …

This study tested the safety of swapping out one drug (cyclophosphamide) for another (bendamustine) in the days following a bone marrow transplant. It involved 50 patients with various blood cancers who needed a transplant but lacked a perfectly matched donor. The goal was to see…

This first-in-human study tested a new oral medication called LP-118 in patients with advanced cancers that had stopped responding to other treatments. The main goals were to find a safe dose, see how the body processes the drug, and check for early signs that it might help contr…

This study tested the safety and initial effectiveness of a two-drug combination (favezelimab and pembrolizumab) for people with certain blood cancers, including Hodgkin lymphoma and non-Hodgkin lymphoma. It involved 137 participants to find a safe dose and see if the treatment c…

This was the first human study of a new experimental drug called JNJ-75348780 for people with advanced non-Hodgkin lymphoma or chronic lymphocytic leukemia that has returned or stopped responding to other treatments. The main goals were to find a safe dose and understand the drug…

This study tested an oral medication called LOXO-305 in Chinese adults with certain types of lymphoma or chronic leukemia that had returned or stopped responding to standard treatments. The main goal was to see how safe the drug was and how well it worked to control the cancer. R…

This study aims to gather information on how well a cancer treatment called CAR T-cell therapy works for people living with HIV who also have certain blood cancers. Researchers will collect standard medical data from about 30 patients who have already received this therapy. The g…

This study aimed to understand why patients with the same type of blood cancer, like lymphoma or leukemia, can have very different outcomes. Researchers analyzed the genes in old tissue samples from 1,340 patients to see if they could find patterns that predict how the disease wi…