New hope for tough lymphomas: experimental drug TLN-121 enters human testing

NCT ID NCT07082803

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This early-stage trial is testing a new drug called TLN-121, alone or with other treatments, in about 180 people whose Non-Hodgkin Lymphoma has returned or not responded to prior therapies. The main goals are to check the drug's safety and how the body processes it, while also looking for signs that it shrinks tumors. Participants must have certain types of lymphoma that have not improved after at least two prior treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BC Cancer - Vancouver

    RECRUITING

    Vancouver, British Columbia, V5Z 4E6, Canada

    Contact Email: •••••@•••••

  • Cabrini Health

    RECRUITING

    Malvern, Victoria, 3144, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Linear Clinical Research

    RECRUITING

    Perth, Western Australia, 6009, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Macquarie University Hospital

    RECRUITING

    Macquarie Park, New South Wales, 2113, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Email: •••••@•••••

  • Peter MacCallum Cancer Centre

    RECRUITING

    Melbourne, Victoria, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Princess Alexandra Hospital

    RECRUITING

    Woolloongabba, Queensland, 4102, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford Medicine Cancer Center

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The START Center for Cancer Care - Midwest

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63108, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.