LEUKEMIA

This study tested a treatment to help prevent acute myeloid leukemia (AML) from returning after initial remission. For patients aged 60 or younger, doctors used high-dose chemotherapy and radiation to wipe out the bone marrow, then gave back the patient's own previously collected…

This study tested whether adding the drug ruxolitinib to standard chemotherapy could help children with a particularly aggressive form of acute lymphoblastic leukemia (ALL). It involved 171 children and young adults (ages 1-21) who had specific genetic markers that make their can…

This study tested a new oral drug called pelabresib for people with advanced blood cancers like myelofibrosis. The first part aimed to find a safe dose. The second part tested if pelabresib, given alone or with another drug (ruxolitinib), could shrink enlarged spleens, reduce the…

This study aimed to find the best way to give a crucial drug called asparaginase to children with acute lymphoblastic leukemia (ALL). It directly compared a newer, longer-lasting version given by IV with the standard version given by injection. The main goal was to see which meth…

This study tested a two-step stem cell transplant method for patients with high-risk blood cancers like leukemia and lymphoma. It used a drug called cyclophosphamide before the transplant to help prevent a dangerous complication called graft-versus-host disease. The goal was to i…

This study tested a new, targeted form of radiation therapy combined with chemotherapy and a donor stem cell transplant for adults with acute leukemia that had not responded well to standard treatments. The main goals were to find the safest dose of the new radiation and to see i…

This study tested whether the drug dasatinib could help control chronic lymphocytic leukemia (CLL), a type of blood cancer. Seventeen patients who had previously received other treatments took dasatinib pills twice daily. Researchers monitored how well the cancer responded and ch…

This study tested a modified three-drug combination given to patients before a stem cell transplant from a partially matched or cord blood donor. The goal was to see if this adjusted regimen could improve survival and reduce severe side effects for people with high-risk blood can…

This study tested if paying for blood transfusions would help people with advanced blood cancers choose hospice care earlier. Patients often delay hospice because they need transfusions, which hospice usually doesn't cover. The research provided free transfusions to see if this h…

This study tested a mobile app program designed to help young adult cancer survivors manage their health after treatment. It aimed to reduce cancer-related distress and improve how well survivors follow recommended health check-ups. Researchers compared the app to standard online…

This study tested whether a peer support group is a helpful and practical way to support young adults (ages 18-39) who have received a stem cell transplant for conditions like leukemia. The main goal was to see if patients found the program useful and easy to participate in. Rese…

This study aims to gather information on how well a cancer treatment called CAR T-cell therapy works for people living with HIV who also have certain blood cancers. Researchers will collect standard medical data from about 30 patients who have already received this therapy. The g…

This study aimed to understand why patients with the same type of blood cancer, like lymphoma or leukemia, can have very different outcomes. Researchers analyzed the genes in old tissue samples from 1,340 patients to see if they could find patterns that predict how the disease wi…

This study aimed to understand how CAR-T cell therapy, a powerful cancer treatment, affects the heart. Researchers followed 44 adults with leukemia or lymphoma, checking their heart function with scans and blood tests before and after treatment. The goal was to learn how often he…

This study aimed to understand if exposure to pesticides increases a child's risk of developing leukemia. Researchers compared 629 children in California, collecting dust samples from their homes and mapping nearby farms to measure pesticide levels. The goal was to see if living …

This study aimed to understand why farmers have higher rates of certain blood cancers. Researchers collected blood and urine samples from nearly 2,000 cancer-free male farmers over age 50 to look for early warning signs. They compared these signs to the farmers' pesticide use his…

This study aimed to identify what helps older adults recover well after a bone marrow transplant for blood cancers like leukemia and lymphoma. Researchers measured physical ability, mental health, stress hormones, and other factors in 126 patients aged 60 and older before and aft…