LEUKEMIA

This study tested a new way to prepare people with hard-to-treat acute leukemia for a donor stem cell transplant. It combined a precise type of radiation (IMRT) with two chemotherapy drugs (etoposide and cytoxan) to kill cancer cells and help the body accept the donor cells. The …

This study tested a combination of chemotherapy drugs in 318 adolescents and young adults (ages not specified but typical for this group) with newly diagnosed acute lymphoblastic leukemia (ALL). The goal was to see how well the treatment worked at killing cancer cells and stoppin…

This study tested the drug dasatinib in 17 people with chronic lymphocytic leukemia (CLL) who had already tried other treatments. The goal was to see if dasatinib could shrink or control the cancer. Researchers measured how many patients had a complete or partial response using s…

This study looked at adding the targeted drug ruxolitinib to standard chemotherapy for children with a high-risk form of acute lymphoblastic leukemia (ALL). The goal was to see if the combination is safe and helps keep the cancer from coming back. The study included 171 children …

This study tested whether enasidenib, a drug typically used for a different genetic type of leukemia, could safely improve anemia and reduce the need for blood transfusions in 17 people with lower-risk myelodysplastic syndrome (MDS) or chronic myelomonocytic leukemia (CMML) who d…

This study looked at 800 children with acute lymphoblastic leukemia to compare two forms of the drug asparaginase: a pegylated version given through a vein and a standard version given as a shot. The goal was to see which caused fewer serious side effects like allergic reactions,…

This study tested a treatment for adults with acute myeloid leukemia (AML) who were in their first remission. Patients received high-dose chemotherapy and radiation, followed by a transplant of their own stem cells, plus an immune-boosting drug to help prevent relapse. The goal w…

This study tested a new pill called pelabresib in people with certain blood cancers, including myelofibrosis and leukemia. The goal was to see if it could shrink enlarged spleens and reduce the need for blood transfusions. The drug was given alone or with another medicine (ruxoli…

This study tested a two-step stem cell transplant using a drug called cyclophosphamide to lower the risk of graft-versus-host disease (GVHD) in people with high-risk blood cancers like leukemia and lymphoma. 47 patients received a transplant from a matched sibling donor. The goal…

This study tested adding a drug called thiotepa to the usual chemo given before a donor stem cell transplant for people with leukemia. The goal was to see if this stronger mix could help more patients stay cancer-free one year later. The trial involved 40 patients and focused on …

This study looked at whether covering the cost of blood transfusions would encourage people with blood cancers to enroll in hospice earlier. Many patients delay hospice because they need regular transfusions for symptom relief, which hospices often can't afford. The study offered…

This study looked at whether a home-based exercise program is practical for people aged 65 and older with lymphoma, leukemia, or myeloma who are about to receive CAR-T cell therapy. Twenty participants were asked to do supervised resistance training and moderate aerobic exercise.…

This study watched 44 adults with leukemia or lymphoma who were getting CAR T-cell therapy. Researchers checked their heart health before and after treatment using heart scans and blood tests. The goal was to see how often heart problems happen and who might be at higher risk.

This study looked at nearly 1,900 male farmers over 50 to see if pesticides are linked to early signs of blood cancers like multiple myeloma. Researchers collected blood and urine samples and asked about pesticide use. No treatment was given—the goal was simply to gather informat…

This study looked back at 30 people with HIV who had already received CAR T-cell therapy for certain blood cancers. Researchers collected standard medical data to see what side effects occurred and how the immune system changed over time. The goal was to learn more about safety a…

This study tested a program designed to help adolescent and young adult cancer survivors (ages 15-39) find and use healthcare resources after treatment. The goal was to improve their health knowledge, self-care skills, and support, and to reduce cancer-related distress. 549 survi…

This study looked at whether pesticides in homes or farms increase the risk of childhood leukemia. Researchers collected carpet dust and mapped nearby crops for 629 children in California. The goal was to see if certain chemicals are linked to higher leukemia rates.

This study looked at 126 adults aged 60 and older who had a bone marrow transplant for blood cancers like leukemia or lymphoma. Researchers measured physical and mental traits—like strength, memory, mood, and stress—to see which factors help people recover better. The goal was to…

This study looked at the genes of over 1,300 people with blood cancers like lymphoma, leukemia, and multiple myeloma. The goal was to find genetic patterns that could explain why some patients respond well to treatment while others do not. Researchers used stored tissue samples a…

This study looked at whether a peer support group is practical and helpful for young adults (ages 18-39) who have had a stem cell transplant. Thirteen participants joined the program, and researchers measured how acceptable and useful it was. The goal was to see if this kind of s…