Leukemia drug showdown: which asparaginase is safer for kids?
NCT ID NCT00400946
First seen Feb 17, 2026 · Last updated May 08, 2026 · Updated 11 times
Summary
This study looked at 800 children with acute lymphoblastic leukemia to compare two forms of the drug asparaginase: a pegylated version given through a vein and a standard version given as a shot. The goal was to see which caused fewer serious side effects like allergic reactions, pancreatitis, or blood clots, and whether one led to better long-term survival. The results help doctors choose the safest and most effective treatment for children with this type of leukemia.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Albert Einstein Cancer Center at Albert Einstein College of Medicine
The Bronx, New York, 10461, United States
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Centre de Recherche du Centre Hospitalier de l'Universite Laval
Sainte-Foy, Quebec, GIV 4G2, Canada
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Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Hasbro Children's Hospital
Providence, Rhode Island, 02903, United States
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Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center
New York, New York, 10032, United States
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Hopital Sainte Justine
Montreal, Quebec, H3T 1C5, Canada
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James P. Wilmot Cancer Center at University of Rochester Medical Center
Rochester, New York, 14642, United States
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McMaster Children's Hospital at Hamilton Health Sciences
Hamilton, Ontario, L8N 3Z5, Canada
Conditions
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