DRUG/AGENT TOXICITY BY TISSUE/ORGAN
Clinical trials for DRUG/AGENT TOXICITY BY TISSUE/ORGAN explained in plain language.
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New oral cocktail aims to tame resistant childhood cancer
Disease control CompletedThis early-stage trial tested a combination of two chemotherapy drugs (irinotecan and temozolomide) plus an antibiotic (cefixime) in 30 children whose high-risk neuroblastoma had come back or not responded to treatment. The main goal was to find the safest dose of oral irinotecan…
Matched conditions: DRUG/AGENT TOXICITY BY TISSUE/ORGAN
Phase: PHASE1 • Sponsor: New Approaches to Neuroblastoma Therapy Consortium • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Leukemia drug showdown: which asparaginase is safer for kids?
Disease control CompletedThis study looked at 800 children with acute lymphoblastic leukemia to compare two forms of the drug asparaginase: a pegylated version given through a vein and a standard version given as a shot. The goal was to see which caused fewer serious side effects like allergic reactions,…
Matched conditions: DRUG/AGENT TOXICITY BY TISSUE/ORGAN
Phase: PHASE3 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 11, 2026 20:49 UTC