LEUKEMIA

This study tested a two-drug combination (ibrutinib followed by venetoclax) in 30 adults with chronic lymphocytic leukemia (CLL) that had returned or stopped responding to prior treatment. The goal was to see if the drugs could work together to clear cancer cells from the body an…

This study tested a drug called eltrombopag to help people whose bone marrow doesn't recover well after a stem cell transplant for leukemia. The goal was to raise platelet counts and reduce the need for transfusions. The trial was stopped early after enrolling only 9 participants…

This study tested the drug ponatinib in 51 adults with a fast-growing form of chronic myeloid leukemia (CML) who had little or no prior treatment. The goal was to see if ponatinib could control the disease by blocking a protein that drives leukemia growth. However, the drug can c…

This study tested a new cell therapy called GDX012 in 16 people with acute myeloid leukemia (AML) that returned or didn't respond to treatment. The main goals were to check safety and find the best dose. The trial was stopped early, so results are limited, but the approach aims t…

This study tested whether adding the drug ponatinib to a standard chemotherapy mix plus venetoclax could help people whose T-cell acute lymphoblastic leukemia (T-ALL) had come back or stopped responding to treatment. Only 4 people took part before the study was stopped early. The…

This study tested whether the drug ofatumumab could control small amounts of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that remain after chemotherapy. It enrolled only 4 adults who had finished chemo but still had signs of disease. The study was termi…

This study tested whether combining two drugs, CB-103 and venetoclax, could help control T-cell acute lymphoblastic leukemia (T-ALL) in teens and young adults whose cancer had returned or not responded to prior treatment. Only 2 participants were enrolled before the trial was sto…

This study tested a digital tool that appears on the lock screen of an Android phone to encourage physical activity in cancer survivors. Participants used the app and wore a Fitbit for 3 months, with follow-up at 6 months. The goal was to see if the app could increase activity an…

This study aimed to see if an oral (pill) form of the drug cladribine works similarly to the standard IV (intravenous) version in people with certain blood cancers like leukemia. Only 3 adults were enrolled before the study was stopped early. The main goal was to check safety and…

This study created a registry for people who survived cancer as young adults (ages 18-39). Researchers wanted to understand their levels of depression, anxiety, social support, and financial stress. Participants filled out online surveys every 6 to 12 months. The registry also he…