LEUKEMIA

This trial tested a two-drug combination (ibrutinib and venetoclax) for adults with chronic lymphocytic leukemia (CLL) that had returned or stopped responding to prior treatment. The goal was to see if using the drugs together could achieve a deep remission, potentially allowing …

This study tested whether the drug ofatumumab could control chronic lymphocytic leukemia or small lymphocytic lymphoma that remained after patients completed chemotherapy. Participants received up to 20 infusions over two years to target residual cancer cells. The trial was termi…

This study tested whether the drug ponatinib could control an aggressive form of chronic myeloid leukemia when used as the first treatment. It involved 51 adults with newly diagnosed advanced leukemia. The trial was terminated early, and the drug carries a serious risk of causing…

This study tested if a drug called eltrombopag could help patients whose blood cell counts remained dangerously low after a stem cell transplant for leukemia, a condition known as poor graft function. The goal was to see if the drug could boost platelet, red blood cell, and white…

This study tested whether combining two drugs, CB-103 and venetoclax, could help control a hard-to-treat type of blood cancer called T-cell acute lymphoblastic leukemia (T-ALL) in adolescents and young adults. The trial was for patients aged 12 to 60 whose cancer had returned or …

This study tested whether a special app on an Android phone could help cancer survivors become more physically active and improve their heart and blood vessel health. Participants were asked to use the app and wear a Fitbit for 3 months, with follow-up checks at 3 and 6 months. T…

This study created a registry to learn about the long-term health and wellbeing of young adults who survived cancer. It aimed to measure their levels of anxiety, depression, social support, and financial stress over time. Participants completed online surveys every 6-12 months to…