Experimental cell therapy for tough leukemia shows early promise but trial halted

NCT ID NCT05886491

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial tested a new cell therapy called GDX012 in 16 people with acute myeloid leukemia (AML) that had come back or not responded to standard treatment. The main goals were to check safety, find the best dose, and see if the therapy could control the cancer. The study was terminated early, so results are limited.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Comprehensive Cancer Center of Northwestern University

    Chicago, Illinois, 60611, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • National Cancer Center Hospital East

    Kashiwa, 277-8577, Japan

  • Sarah Cannon/CBCI

    Denver, Colorado, 80218, United States

  • Thomas Jefferson University

    New York, New York, 10065, United States

  • Tri-Star BMT/Sarah Cannon Nashville

    Nashville, Tennessee, 37203, United States

  • University of Alabama at Birmingham (UAB) Hospital

    Birmingham, Alabama, 35205, United States

  • Washington University

    St Louis, Missouri, 63110, United States