IRREVERSIBLE PULPITIS
Clinical trials for IRREVERSIBLE PULPITIS explained in plain language.
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Ancient toothbrush plant tested as a modern pulp saver
Disease control Not yet recruitingThis study tests whether a paste made from Salvadora persica (a plant used in traditional toothbrushes) mixed with zinc oxide can work as well as the standard material (MTA) for treating severe tooth inflammation. The trial involves 78 adults aged 18-40 with infected permanent mo…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: Postgraduate Medical Institute, Lahore • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Rosemary vs. root canal: could a kitchen herb save your tooth?
Disease control Not yet recruitingThis study compares rosemary extract to a standard material (MTA) for treating severe tooth pulp inflammation. Researchers will treat 100 adults with a damaged tooth, placing either rosemary extract or MTA directly on the pulp. They will then measure pain and healing over time to…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: University of Health Sciences Lahore • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New spinning tool may beat manual cleaning for kids' tooth infections
Disease control Not yet recruitingThis study tests whether a single rotary file system removes more bacteria from infected baby molars than traditional manual files. Thirty-four children aged 4 to 6 with irreversible pulpitis will have their root canals cleaned using one of the two methods. The main goal is to me…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Could a simple pulpotomy replace root canals for some patients?
Disease control Not yet recruitingThis study compares two treatments for irreversible pulpitis, a condition causing severe tooth pain. The standard treatment is a root canal, but researchers want to see if a less invasive procedure called pulpotomy works just as well. The study will involve 138 people and also lo…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New Tooth-Saving technique could spare teens from root canals
Disease control Not yet recruitingThis study tests if a less invasive procedure called partial pulpotomy using CGF (a blood concentrate) can control pain and inflammation in severely decayed permanent molars as well as standard root canal treatment. It will involve 60 adolescents aged 11-17 with intense tooth pai…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: Minia University • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New study tests faster way to fix kids' tooth infections
Disease control Not yet recruitingThis study looks at two methods for cleaning and filling infected baby molars in children aged 5-7. One method uses a manual tool, the other a rotating tool. The goal is to see which works better over a year. About 44 children will take part.
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: Anfal mohamed elmotaz almogtaba • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Can a cold blast save your tooth? new trial investigates cryotherapy for deep cavities
Disease control Not yet recruitingThis study looks at whether applying cold (cryotherapy) during a pulpotomy—a procedure that removes infected nerve tissue from a tooth—improves the chance of saving the tooth. Researchers will compare treatment success in 140 healthy adults with deep cavities. Success means no pa…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: EARLY_PHASE1 • Sponsor: Sirawut Hiran-us • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Root canal relief? study tests weaker bleach for less pain
Symptom relief Not yet recruitingThis study compares two strengths of sodium hypochlorite (a disinfectant used during root canals) to see which causes less pain afterward. 116 adults needing a root canal will be randomly assigned to receive either a 2.5% or 5.25% solution. Pain levels will be measured at 6, 12, …
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: College of Physicians and Surgeons Pakistan • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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Microscope magic? new study tests if High-Tech view saves more teeth
Symptom relief Not yet recruitingThis study compares two ways of doing a pulpotomy (a type of root canal) for adults with a painful, infected tooth. Half the treatments will use a special dental microscope, and half will not. The goal is to see if the microscope helps the tooth heal better over time. Fifty healt…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: EARLY_PHASE1 • Sponsor: Chulalongkorn University • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New tool may ease pain after baby tooth root canals
Symptom relief Not yet recruitingThis study tests whether using a special rotary file (a spinning tool) causes less pain after a baby tooth root canal than the traditional manual file. Fifty children aged 4 to 6 with an infected baby molar will be randomly assigned to one of the two methods. Parents will rate th…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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New study tests if a faster drill makes kids less scared at the dentist
Symptom relief Not yet recruitingThis study looks at whether using a special rotating tool (rotary file) instead of a hand tool (manual file) during a baby molar root canal (pulpectomy) makes children behave better. It will include 54 children aged 4-6 who need this treatment. The main goal is to see if the rota…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Cold therapy may ease root canal pain, new study suggests
Symptom relief Not yet recruitingThis study tests whether applying cold (cryotherapy) to the gums right after a numbing shot can make root canal treatment less painful. About 100 adults with an infected lower premolar tooth will be randomly assigned to receive standard numbing methods with or without the cold tr…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: TC Erciyes University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Root canal showdown: which sealer hurts less?
Symptom relief Not yet recruitingThis study aims to find out which of two root canal sealers causes less pain after treatment. Sixty adults with tooth nerve inflammation will have root canals and then rate their pain over two days. The goal is to improve patient comfort and recovery.
Matched conditions: IRREVERSIBLE PULPITIS
Phase: PHASE2, PHASE3 • Sponsor: Jaweria Gul Keyani • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC