Root canal relief? study tests weaker bleach for less pain
NCT ID NCT07618182
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two strengths of sodium hypochlorite (a disinfectant used during root canals) to see which causes less pain afterward. 116 adults needing a root canal will be randomly assigned to receive either a 2.5% or 5.25% solution. Pain levels will be measured at 6, 12, 24, and 48 hours after treatment using a simple pain scale.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sodium hypochlorite
- What this could lead to
- If it works, this could show that a lower concentration of sodium hypochlorite reduces pain after root canal treatment while still cleaning the tooth effectively.
- What could go wrong
- This is a small, early-stage trial with only 116 participants. The results may not apply to everyone, and the difference in pain between the two concentrations might be small or not meaningful.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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