Ancient toothbrush plant tested as a modern pulp saver
NCT ID NCT07630181
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a paste made from Salvadora persica (a plant used in traditional toothbrushes) mixed with zinc oxide can work as well as the standard material (MTA) for treating severe tooth inflammation. The trial involves 78 adults aged 18-40 with infected permanent molars. Researchers will check for pain, swelling, and signs of infection over six months to see if the natural alternative is a viable, low-cost option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Salvadora persica extract mixed with zinc oxide powder
What this could lead to
If successful, this natural and low-cost material could offer an accessible alternative to standard treatments for saving infected teeth, especially in low-resource settings.
What could go wrong
This is a small, early-stage trial with only 78 participants and a short 6-month follow-up. The natural extract may not perform as well as the standard material, and long-term outcomes are unknown.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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de Montmorency college of dentistry lahore
Lahore, Punjab Province, 54000, Pakistan
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••