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Pill or injection? trial tests which piroxicam method best eases root canal pain

NCT ID NCT07712991

Completed Symptom relief Sponsor: Pakistan Institute of Medical Sciences Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This trial compares two ways of giving the anti-inflammatory drug piroxicam to control pain after root canal treatment: a standard oral pill versus an injection into the ligament around the tooth. Adults with a toothache caused by irreversible pulpitis will receive one of the two methods and rate their pain after 12, 24, and 48 hours. The goal is to find out which approach provides better pain relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
piroxicam given by mouth or injected into the ligament around the tooth
What this could lead to
If one method proves better, it could give dentists a more effective way to manage pain after root canal treatment.
What could go wrong
This is a small, single-center trial with only 50 participants, so results may not apply to everyone. Pain is subjective and hard to measure precisely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia Pain pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAIN MANAGEMENT POST ENDODONTIC PAIN

Contacts and locations

Locations

  • Pakistan Institute of Medical Sciences

    Islamabad, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.