IRREVERSIBLE PULPITIS
Clinical trials for IRREVERSIBLE PULPITIS explained in plain language.
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Could a tooth's own pulp be used to regenerate root canals?
⭐️ CURE ⭐️ TerminatedThis trial tests whether transplanting a patient's own minced pulp tissue into a cleaned root canal can regenerate living dental pulp. Fifty participants aged 7 to 50 with infected or inflamed teeth will receive either standard root canal treatment or the experimental tissue tran…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: University of California, Los Angeles • Aim: ⭐️ CURE ⭐️
Last updated Jul 25, 2026 00:00 UTC
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Can a simpler procedure save children's aching baby teeth?
Disease control OngoingThis trial tests whether a less invasive dental procedure called pulpotomy can successfully treat baby molars with a severe, painful tooth condition known as irreversible pulpitis. Instead of removing the entire nerve, pulpotomy removes only the top part and places a soothing med…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: Qatar University • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Could a simpler tooth procedure spare kids from root canals?
Disease control TerminatedThis study compares two dental procedures for treating severe pulpitis (tooth nerve inflammation) in children's baby molars. One is a standard full root canal treatment (pulpectomy), and the other is a less invasive option that removes only part of the nerve (pulpotomy). The goal…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: Nebu Philip • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Green tea extract may ease tooth pain after Root-Saving procedure
Symptom relief OngoingThis study looks at whether rinsing with a green tea extract (EGCG) during a tooth-saving procedure (pulpotomy) can lower pain and improve success rates in adults with severe tooth decay. 64 participants with deep cavities will receive one of two rinses and one of two filling mat…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Laser or ultrasound: which root canal method hurts less?
Symptom relief OngoingThis study tests two ways to clean a tooth during a root canal: laser-activated irrigation and passive ultrasonic irrigation. Researchers want to see which method leads to less pain and better quality of life afterward. 90 adults with infected or damaged permanent teeth are takin…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: Chulalongkorn University • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Tooth pain relief: steroid injection may beat placebo after root canal
Symptom relief OngoingThis study tests whether a single injection of dexamethasone (a steroid) near the tooth can reduce pain after root canal treatment for people with severe, irreversible tooth inflammation. 44 adults with this condition will receive either the steroid or a placebo (salt water) inje…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: College of Physicians and Surgeons Pakistan • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Which Tooth-Shaving method keeps your tooth coolest?
Knowledge-focused OngoingThis study measures how hot the inside of a tooth gets when dentists shave off a tiny bit of enamel (a common step before braces). Researchers will test two different tools on 40 teeth from 30 people to see which method causes less heat. Keeping the tooth cool is important becaus…
Matched conditions: IRREVERSIBLE PULPITIS
Phase: NA • Sponsor: Armed Forces Institute of Dentistry, Pakistan • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Blood markers may predict why your dental numbing fails
Knowledge-focused OngoingThis study looks at whether certain inflammation markers in the blood can predict how well dental numbing shots work and how much pain people feel after treatment. Researchers will analyze blood samples from 150 adults with tooth inflammation (irreversible pulpitis) and compare t…
Matched conditions: IRREVERSIBLE PULPITIS
Sponsor: KEZBAN MELTEM ÇOLAK • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:53 UTC