Could a simple pulpotomy replace root canals for some patients?
NCT ID NCT04922229
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two treatments for irreversible pulpitis, a condition causing severe tooth pain. The standard treatment is a root canal, but researchers want to see if a less invasive procedure called pulpotomy works just as well. The study will involve 138 people and also look for biomarkers that predict success.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pulpotomy procedure
What this could lead to
If successful, this could show that a simpler, less invasive tooth-saving procedure works as well as a root canal for certain cases of severe tooth pain.
What could go wrong
This is a small, early-stage study that hasn't started yet. The pulpotomy may not be as effective long-term as the standard root canal, and results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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School of Dentistry, University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••