Could a simple pulpotomy replace root canals for some patients?

NCT ID NCT04922229

Not yet recruiting Disease control Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two treatments for irreversible pulpitis, a condition causing severe tooth pain. The standard treatment is a root canal, but researchers want to see if a less invasive procedure called pulpotomy works just as well. The study will involve 138 people and also look for biomarkers that predict success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pulpotomy procedure
What this could lead to: If successful, this could show that a simpler, less invasive tooth-saving procedure works as well as a root canal for certain cases of severe tooth pain.
What could go wrong: This is a small, early-stage study that hasn't started yet. The pulpotomy may not be as effective long-term as the standard root canal, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for IRREVERSIBLE PULPITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IRREVERSIBLE PULPITIS

Contacts and locations

Locations

School of Dentistry, University of Alabama at Birmingham

Birmingham, Alabama, 35233, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.