INFECTIONS

This study tested whether giving a common antibiotic (piperacillin-tazobactam) as a longer, slower infusion is a practical way to research better dosing for people with obesity. It involved 45 hospitalized adults with obesity who needed this antibiotic. The main goal was to see i…

This study tested an experimental drug called vapendavir to see if it could reduce serious lung symptoms in people with COPD after they caught a common cold virus. Researchers gave the drug or a placebo to 52 adults with moderate COPD who were then exposed to the virus. The main …

This study tested whether providing full hospital-level medical care in patients' own homes is a safe and effective alternative to traditional hospital stays for rural adults. It involved 160 adults with serious but manageable conditions like severe infections, heart failure, COP…

This early-stage study tested a new oral drug, MMV367, for malaria. Researchers deliberately infected 12 healthy adult volunteers with malaria parasites to see how the drug is processed by the body and how well it kills the parasites. The main goal was to understand the relations…

This study tested new portable sensor devices designed to quickly identify infections like COVID-19, Pseudomonas bacteria, and Leishmania parasites in blood and respiratory samples. Researchers compared these new devices to standard lab tests to see if they are accurate, fast, an…

This study tested whether using a special antiseptic dressing on the tubes of ECMO life support could prevent serious infections. It involved 270 critically ill adults with heart or lung failure who were on ECMO. Patients were randomly assigned to receive either the antiseptic dr…

This study tested whether showing patients a short educational video could help prevent serious bloodstream infections. About 1,000 hospitalized patients who needed to use special antiseptic bathing cloths participated. Researchers compared units where patients watched the video …

This study tested whether a special wound dressing (negative pressure wound therapy) could prevent infections better than standard wound closure after emergency abdominal surgery for peritonitis. It involved 50 patients who had this urgent surgery and followed them for a year. Th…

This study tested whether a daily supplement made from cow's colostrum (the first milk) could help prevent recurring urinary tract infections (UTIs) in children. Sixty children with a history of frequent UTIs were randomly assigned to take either the colostrum supplement or a pla…

This study investigated whether people who run extreme long-distance races get sick more often in the weeks after the race. Researchers compared 471 runners in a major ultramarathon event to their non-running companions who lived with them. They tracked symptoms like colds, sore …