INFECTIONS

This study tested an experimental drug called vapendavir in 52 adults with COPD (a chronic lung disease). The goal was to see if the drug could reduce severe cold symptoms caused by rhinovirus, a common cold virus. Participants were given either vapendavir or a placebo and monito…

This study tested whether using a special antiseptic dressing on the tubes that connect patients to an ECMO machine (a heart-lung bypass for critically ill people) can reduce serious infections. About 270 adults on ECMO for heart or lung failure were randomly assigned to get eith…

This study tested whether a special wound vacuum (negative pressure therapy) works better than standard stitches to prevent surgical site infections in 50 patients who had emergency abdominal surgery for peritonitis (a serious belly infection). The main goal was to see which meth…

This study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The main goal was to see if this approach could lower costs and keep p…

This study tested new portable sensor platforms to quickly and cheaply detect three types of infections: SARS-CoV-2 (the virus that causes COVID-19), Pseudomonas aeruginosa bacteria, and Leishmania infantum parasites. Researchers used blood and respiratory samples from 149 adult …

This study tested whether a supplement from cow's first milk (bovine colostrum) could prevent repeat urinary tract infections (UTIs) in 60 children. The goal was to see if this natural product, which contains immune-boosting substances, could be a safe alternative to antibiotics.…

This study tested a new approach to prevent surgical site infections: using a special light treatment inside the nose before surgery. Nearly 4,800 adults having major surgeries (like heart, spine, or breast surgery) took part. Half got the light treatment plus standard care, and …

This study tested a new approach to prevent surgical site infections: using a special light-based treatment (antimicrobial photodisinfection) inside the nose before surgery. The trial involved 401 adults undergoing major surgeries like heart, spine, or breast procedures. Half rec…

This study looked at 351 adults with inguinal hernia who had keyhole surgery (TAPP). Doctors compared using 3 points versus 1 point to fix the mesh inside. The goal was to see which method caused less pain, fewer complications like fluid buildup or infection, and lower chance of …

This study looked at whether running a very long race (an ultratrail) makes people more likely to get infections like colds or sore throats. Researchers compared 471 runners with their companions who did not run. They tracked symptoms for three weeks after the race to see if the …

This study tested a new experimental drug called MMV367 in 12 healthy adults who were intentionally infected with the malaria parasite. The goal was to see how the drug works in the body and how well it clears the parasite. Participants were closely monitored and given standard m…

This study looked at whether giving the antibiotic piperacillin-tazobactam as a longer infusion helps people with obesity reach the right drug level in their blood. It included 45 hospitalized adults with obesity who needed this antibiotic. The main goal was to see if a larger st…

This study tested whether showing hospital patients a short video about CHG bathing helps them follow the correct bathing routine. CHG bathing reduces the risk of serious bloodstream infections from central lines. About 1000 adults took part. The goal was to see if the video impr…