INFECTIONS

This study follows women who previously received the GBS-NN/NN2 vaccine during pregnancy to see how long their immune protection lasts. It also tests whether a booster dose given in a new pregnancy is safe and boosts immunity, aiming to protect newborns from group B strep infecti…

This phase II trial tests whether bevacizumab, a drug that blocks blood vessel growth, can lengthen the time between surgeries for adults with recurrent respiratory papillomatosis (RRP), a rare condition causing wart-like growths in the airways. Participants receive 11 doses of t…

This study looks at whether treating patients at home for conditions like infections, heart failure, diabetes, and COPD can lead to better health outcomes and satisfaction compared to traditional hospital stays. Nearly 10,000 adults will receive hospital-level care at home, inclu…

This study tests whether infant formula with added bioactive ingredients helps healthy babies grow well, tolerate the formula, and have fewer infections. About 456 full-term infants will receive either the test formula or a standard formula. Parents will report any infection symp…

This study looks at 800 children with mild open fractures to see how much antibiotic is needed to prevent infections. Some kids get one dose, some get 24 hours, and some get 24 hours plus five days of pills. The goal is to find the best balance between preventing infection and av…

This study tests if a special parenting program (Attachment Biobehavioral Catch-Up) can help low-income Latino children have fewer common illnesses, better sleep, and healthier weight. About 260 mothers and their 9-month-old babies will take part. The program focuses on strengthe…

This study aims to understand how the immune system responds to a second infection with a mild bird flu virus (H10N7). Healthy adults who were infected with H10N7 in a previous study will be infected again and monitored closely in the hospital for 9 days. The goal is to learn mor…

This study aimed to see if an artificial intelligence system could predict sepsis—a serious infection—in people recovering from abdominal surgery. Researchers planned to use wearable sensors and hospital data to spot early warning signs. However, the study was withdrawn before en…

This study follows over 2,000 people and their pets in the Canton of Bern to learn how infections like COVID-19 spread and what social and environmental factors influence transmission. Participants provide samples and answer questionnaires over time. The goal is to improve pandem…

This study tests a new digital platform that helps doctors and nurses share important patient information when a person is moved from one hospital to another. About 1,000 adults being transferred to a major hospital will take part. The goal is to see if better information sharing…

This study looks at how social factors like poverty and race affect care for mothers with sepsis, a leading cause of death after childbirth in the U.S. Researchers will interview 200 Spanish- or English-speaking women who recently gave birth and had infection warning signs, plus …

This observational study looks at 400,000 birthing people to better predict maternal sepsis, a leading cause of death in the U.S. The goal is to improve risk prediction by considering social factors like poverty and race, and to create a care model that reduces death and disabili…

This study looks at whether taking vitamin D and omega-3 (fish oil) supplements can lower the risk of infections like colds, flu, and urinary tract infections in healthy adults. It also measures a protein called hCAP18, which is part of the body's natural defense against germs. O…