INFECTIONS

This study follows healthy pregnant women who previously received an experimental Group B Streptococcus (GBS) vaccine to see how long their immune protection lasts. It also tests whether a booster dose given during a new pregnancy is safe and boosts immunity, aiming to protect ne…

This study tests if the drug bevacizumab can help adults with a rare condition called recurrent respiratory papillomatosis (RRP), which causes wart-like growths in the airways that often need repeated surgeries. About 21 participants will receive the drug through an IV after surg…

This study looks at whether a new infant formula with added bio-active ingredients helps healthy babies grow well and have fewer infections. About 456 full-term, healthy infants will either get the special formula or a standard one. Parents will report growth, comfort, and any in…

This study looks at whether a single dose of antibiotics works as well as longer courses to prevent infections in children with mild open fractures. About 800 kids aged 0-17 with grade 1 or 2 open fractures will be split into three groups: one dose, 24 hours, or 24 hours plus 5 d…

This study looks at whether taking vitamin D and omega-3 supplements can reduce the risk of infections like colds, flu, and urinary tract infections in healthy adults. It involves over 25,000 participants from a larger heart and cancer prevention trial. Researchers will also meas…

This study is watching how infections like COVID-19 spread among people and between people and their pets in the Canton of Bern. Researchers want to learn what social and environmental factors make it easier for diseases to spread. Over 2,100 people are taking part by answering s…

This study was designed to see if an artificial intelligence (AI) system could predict sepsis—a serious infection—in patients recovering from abdominal surgery. Participants would have worn a non-invasive device on their finger to track vital signs, and the AI would combine that …

This study aims to understand how the immune system reacts to a second infection with a mild bird flu strain (H10N7). Healthy adults who were infected with H10N7 in a previous study will be re-infected via a nasal spray and monitored in the hospital for at least 9 days. The goal …

This study looks at whether treating patients at home, instead of in a hospital, can lead to better health outcomes and happier patients. About 9,654 adults with conditions like heart failure, infections, or diabetes will receive hospital-level care in their own homes. Researcher…

This study looks at the health records of 400,000 birthing people to find better ways to predict and prevent maternal sepsis, a leading cause of death during and after childbirth. It focuses on understanding how social factors like poverty and race affect risk, especially for Bla…

This study tests a new digital tool that helps hospitals share patient information more reliably when a person is transferred from one hospital to another. The goal is to reduce medical mistakes and improve safety. About 1,000 adults being transferred to a major hospital will tak…

This study looks at how social factors like poverty and race affect care for new mothers with sepsis, a leading cause of maternal death in the U.S. Researchers will interview 200 patients and community experts to understand their experiences and improve care. The goal is to creat…