HIV/AIDS

This study looked at 447 people with advanced HIV to compare two types of combination treatments: one with a boosted protease inhibitor and one with an integrase inhibitor. The goal was to see which works better and has fewer side effects for late presenters. Results could help d…

This study tested a mobile app version of the 'Getting Off' program for gay and bisexual men who use methamphetamine. The app offers games, lessons, and resources to help reduce drug use and risky sexual behaviors. 226 men participated, and the study measured changes in meth use,…

This study looked at whether giving HIV-infected infants (aged 1 month to 1 year) early treatment for two common infections—cytomegalovirus (CMV) and tuberculosis (TB)—could help them survive severe pneumonia. Over 560 babies participated across multiple hospitals. The goal was t…

This study tested a 4-session program called PARTNER for young men who have sex with men (ages 18-29) in relationships. The program used motivational interviewing to help them take PrEP (a daily pill to prevent HIV), reduce risky sex, and cut down on drug use. 196 men took part, …

This study tested a new HIV medication (Biktarvy) taken twice daily in 122 adults who also have drug-sensitive tuberculosis (TB) and are on standard TB treatment. The main goal was to see if the drug could suppress HIV to undetectable levels by week 24. Results help doctors under…

This study tested two types of counseling—brief and in-depth—against usual care to help 680 people living with HIV in Zambia reduce unhealthy alcohol use and improve mental health. The goal was to see if these therapies help more people achieve HIV viral suppression (a low level …

This study tested whether a mobile van that offers HIV prevention and treatment services, linked to a needle exchange program, can improve health outcomes for people who inject drugs. Researchers enrolled 720 participants and measured access to services, risk behaviors, and healt…

This study tested a mobile app called PeerNaija that sends medication reminders, shows personal and anonymous peer adherence scores, and offers monthly lottery prizes to encourage young people living with HIV in Nigeria to take their medicine regularly. Fifty-four participants ag…

This study tested a short counseling program called Acceptance-Based Behavior Therapy (ABBT) for people newly diagnosed with HIV. The goal was to help them keep up with their medical appointments and take their HIV medication regularly. 38 adults with HIV took part, and the study…

This study tested a smartphone app called LetSync designed to help Black men who have sex with men and their partners stay engaged in HIV care and take their medications as prescribed. About 144 participants (80 couples) used the app for up to 14 months. The goal was to see if th…

This study tested whether bringing together groups of friends who all have HIV can help them support each other to stay in medical care and take their medication. Over 300 people in St. Petersburg, Russia, took part. The approach aimed to improve viral load, clinic visits, and me…

This study tested a program where trained peers (other women with HIV) provided education and support to pregnant women living with HIV. The goal was to help them stay in medical care and keep the virus under control during the first year after giving birth. 151 women participate…

This study tested a program to help HIV-positive men who have sex with men (MSM) who also struggle with substance use and feel stigmatized. The goal was to see if a special emotion-regulation program could help them stay engaged in HIV care. Fifty participants completed the progr…

This study tested whether a problem-solving program delivered by video calls and text messages could help young people aged 18-29 living with HIV stay engaged in care, improve mental health, and reduce substance use. Fifty participants from the East Bay area of San Francisco took…

This study tested whether blocking the hormone aldosterone and boosting another hormone called BNP could reduce early heart damage in people with HIV. 39 participants with well-controlled HIV and signs of early heart stress received the treatment. The goal was to see if this appr…

This study looked at two different ways to help people living with both HIV and high blood pressure in Uganda. The goal was to see which method works better to control blood pressure and save lives. Over 87,000 adults from HIV clinics took part, and researchers compared a simpler…

This study tested a counseling program called CETA for women with HIV who had experienced intimate partner violence and had unsuppressed virus levels. About 399 women in South Africa took part, receiving either CETA or standard care. The goal was to see if CETA could help more wo…

This study looked at whether bringing HIV and chronic disease care into the community and linking it with microfinance groups helps people with HIV stay in care and keep the virus under control. About 1,200 adults in rural Kenya took part. The goal was to see if this combined app…

This study looked at 114 HIV/AIDS patients in the hospital with an opportunistic infection. It compared starting antiretroviral therapy (ART) within 48 hours versus waiting until the infection was under control. The goal was to see which timing reduced deaths. The study is comple…

This study tested whether an economic empowerment program could reduce alcohol and drug use among adolescents and young adults (ages 15-24) living with HIV in poor communities in Uganda. The 95 participants were already receiving HIV care and had recently used alcohol or drugs. T…

This study tested different ways to help young women in South Africa take their daily HIV prevention pills (PrEP) consistently. 360 women aged 18-25 who were sexually active took part. The goal was to find the best support methods to keep them protected from HIV.

This study tested new ways to help women and men who visit drinking venues in rural Kenya and Uganda start using HIV prevention medications like PrEP. Over 9,000 adults took part, and researchers tracked how many began prevention within a month. The goal was to find effective, lo…

This study tested a simple change in how clinics prescribe TB prevention medicine to people with HIV. Instead of doctors having to choose to prescribe it, the new approach made TB prevention the automatic option unless the doctor decided to opt out. Over 50,000 adults in South Af…

This study tested a program to help healthcare providers prescribe HIV PrEP (a daily pill that prevents HIV) more effectively. The program included a web-based tool and a coordinator to support providers. The study took place in 10 clinics in San Francisco and measured how many P…

This study tested a program called HUG-M+ to help young Thai men who have sex with men get tested for HIV and practice safer sex. About 636 men aged 15-29 took part in two Thai cities. The program aimed to improve HIV testing rates and reduce condomless anal sex over two years.

This study tested a phone app designed to help Black young men who have sex with men (ages 18-29) in Alabama get tested for HIV and learn about prevention. The app offered education, support, and referrals for PrEP, a daily pill that prevents HIV. About 59 people took part, and t…

This study looked at whether giving HIV prevention pills (PrEP) to men who have sex with men in West Africa is acceptable and practical. About 650 HIV-negative men from Burkina Faso, Côte d'Ivoire, Mali, and Togo took part. They could choose daily or on-demand pills, plus other p…

This study tested a new way to help prevent HIV by offering prevention medication (PrEP) to high-risk people in the emergency department. 26 adults who were HIV-negative and medically stable took part. The goal was to see if starting PrEP in the ER helps people get follow-up care…

This study tested two programs to help adolescents aged 10-14 with HIV feel less stigma and shame. One program used group therapy to build coping skills, while the other strengthened family support. The goal was to improve mental health and reduce the negative impact of HIV-relat…

This study tested non-drug methods to reduce nerve pain in the feet and legs of people with HIV. 196 adults with HIV and long-term nerve pain took part. The goal was to see if these approaches could lower pain and improve daily life.

This study tested whether Eye Movement Desensitization and Reprocessing (EMDR) therapy, added to standard HIV care, can reduce psychological trauma and improve quality of life in people recently diagnosed with HIV. Forty adults who were diagnosed within the past month and startin…

This study reviewed health records of 2,039 people from racial/ethnic minority groups who have HIV to see if seeing a heart specialist helps prevent heart disease. Researchers tracked who visited a cardiologist and compared heart outcomes over up to 5 years. The goal is to learn …

This study looked at how to best prevent tuberculosis (TB) in Malaysian prisoners, especially those with opioid addiction and HIV. Researchers compared a standard 9-month daily TB prevention medicine to a shorter 3-month weekly option. The goal was to see which approach works bet…

This study tested different methods of delivering HIV testing and counseling to young male couples (ages 15-24). Researchers wanted to see which approach helped partners communicate better and reduce risky sexual behavior. 71 couples participated, and the study focused on improvi…

This study looked at whether community health workers visiting pregnant women at home in rural South Africa can improve health for both mothers and children. About 1,490 women took part, with some areas getting the home-visit program and others not. The program aimed to help with…

This study looked at how support from friends and family can help teenagers living with HIV stay in care and take their medicine regularly. Researchers worked with 60 teens in South Africa to understand which types of support work best. The goal was to design a better program to …