HIV treatment showdown: which combo works best for Late-Stage patients?
NCT ID NCT03696160
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared two different HIV drug combinations in 447 people with advanced HIV (late presenters). One group received a protease inhibitor combo (Symtuza), the other an integrase inhibitor combo (Biktarvy). The goal was to see which works better and has fewer side effects. Results help doctors choose the best treatment for this group.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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ASST Santi Paolo
Milan, Italy
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Barts Health
London, United Kingdom
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CHU Saint-Pierre
Brussels, Belgium
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CHU de Nantes
Nantes, France
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Chelsea and Westminister
London, United Kingdom
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Clinica of Infectious Diseases
Modena, Italy
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Goethe University Hospital Frankfurt
Frankfurt, Germany
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Groupe Hospitalier Sud Ile-de-France (Melun)
Melun, France
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Guy's Hospital
London, United Kingdom
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Homerton University Hospital
London, United Kingdom
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Hopital Europeen Marseille
Marseille, France
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Hopital Lariboisiere
Paris, France
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Hopital Saint-Louis
Paris, France
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Hospital 12 Octubre
Madrid, Spain
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Hospital Bellvitge
Barcelona, Spain
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Hospital Clinic (Helios Building)
Barcelona, Spain
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Hospital General Universatario Alicante
Alicante, Spain
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Hospital General Universitatrio de Elche
Elche, Spain
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Hospital Ramon y Cajal
Madrid, Spain
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Hospital Trias i Pujol
Barcelona, Spain
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Hospital Universitari Vall d'Herbon
Barcelona, Spain
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Hospital Universitatrio La Paz
Madrid, Spain
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Hospital Virgen de la Victoria
Málaga, Spain
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Hospital de la Princesa
Madrid, Spain
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Hospital de la Santa Creu i Sant Pau
Barcelona, Spain
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Hospital del Mar
Barcelona, Spain
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Hôpital Gui de Chauliac
Montpellier, France
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Hôpital Saint Antoine
Paris, France
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ICH Study Center Gmbh & Co. KG
Hamburg, Germany
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INMI Lazzaro Spallanzani, Rome
Rome, Italy
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Imperial College Healthcare Trust
London, United Kingdom
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Institute of Tropical Medicine
Antwerp, Belgium
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Kings College London
London, United Kingdom
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Leeds Teaching Hospital
Leeds, United Kingdom
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Luigi Sacco Hospital
Milan, Italy
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Mater Misericordiae University Hospital
Dublin, Ireland
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Medizinische Hochschule Hannover
Hanover, Germany
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Medizinische Klinik und Poliklinik Universitätsklinikum Bonn
Bonn, Germany
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Mortimer Market Centre
London, United Kingdom
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North Manchester General Hospital
Manchester, United Kingdom
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Ospedale San Raffaele
Milan, Italy
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Pitié-Salpêtrière Hospital
Paris, France
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Royal Bournemouth Hospital
Bournemouth, United Kingdom
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Royal Free Hospital
London, United Kingdom
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Sheffield Teaching Hospital
Sheffield, United Kingdom
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Southmead Hospital
Bristol, United Kingdom
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St George's Hospital
London, United Kingdom
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St Vincent's University Hospital
Dublin, Ireland
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University Hospital Geissen
Geißen, Germany
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University Hospital Ghent
Ghent, Belgium
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University Hospital Klinikum rechts der Isar der TUM
Munich, Germany
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University Hospital Koln
Cologne, Germany
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University Hospital Lewisham
London, United Kingdom
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