Simple change could save thousands from TB: study tests 'Opt-Out' approach
NCT ID NCT04466488
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a simple way to get more HIV patients in South Africa the medicine that prevents tuberculosis (TB). Instead of doctors having to choose to prescribe it, the new approach made TB prevention the standard option, requiring doctors to actively opt out if they didn't want to give it. Over 50,000 adults from public clinics took part to see if this 'choice architecture' could boost the number of people getting life-saving TB prevention.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HIV/AIDS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Perinatal HIV Research Unit
Soweto, Gauteng, 1864, South Africa
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a robot help stroke survivors with HIV walk again?
- Can coaching clinics curb HIV? a new strategy puts it to the test
- Can a Father-Focused program curb HIV, substance abuse, and violence?
- Can immune profiling unlock the hidden stages of tuberculosis?
- Smart pill bottles and health coaches team up to tackle HIV in the deep south
- Could routine STI screening during pregnancy prevent preterm births?